12-deoxyphorbol 13-phenylacetate 20-acetate
12-deoxyphorbol 13-phenylacetate 20-acetate structure
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Common Name | 12-deoxyphorbol 13-phenylacetate 20-acetate | ||
|---|---|---|---|---|
| CAS Number | 54662-30-5 | Molecular Weight | 508.60300 | |
| Density | 1.29g/cm3 | Boiling Point | 635.7ºC at 760 mmHg | |
| Molecular Formula | C30H36O7 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 204.3ºC | |
| Symbol |
GHS06 |
Signal Word | Danger | |
| Name | 12-deoxyphorbol 13-phenylacetate 20-acetate |
|---|---|
| Synonym | More Synonyms |
| Density | 1.29g/cm3 |
|---|---|
| Boiling Point | 635.7ºC at 760 mmHg |
| Molecular Formula | C30H36O7 |
| Molecular Weight | 508.60300 |
| Flash Point | 204.3ºC |
| Exact Mass | 508.24600 |
| PSA | 110.13000 |
| LogP | 3.32370 |
| Index of Refraction | 1.607 |
| Symbol |
GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H300-H310-H315-H319-H330-H335 |
| Precautionary Statements | P260-P264-P280-P284-P301 + P310-P302 + P350 |
| RIDADR | UN 2811 6.1 / PGIII |
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Phosphorylation of connexin43 and inhibition of gap junctional communication in 12-O-tetradecanoylphorbol-13-acetate-exposed R6 fibroblasts: minor role of protein kinase C beta I and mu.
Carcinogenesis 22(2) , 221-31, (2001) 12-O:-tetradecanoylphorbol-13-acetate (TPA) inhibits gap junctional communication in many cell culture systems, but TPA-induced phosphorylation of the gap junction protein connexin43 (Cx43) varies muc... |
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Protein kinase C modulates insulin action in human skeletal muscle.
Am. J. Physiol. Endocrinol. Metab. 278(3) , E553-62, (2000) There is good evidence from cell lines and rodents that elevated protein kinase C (PKC) overexpression/activity causes insulin resistance. Therefore, the present study determined the effects of PKC ac... |
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Rapid loss of blood-brain barrier P-glycoprotein activity through transporter internalization demonstrated using a novel in situ proteolysis protection assay.
J. Cereb. Blood Flow Metab. 30(9) , 1593-7, (2010) Blood-brain barrier (BBB) P-glycoprotein activity is rapidly reduced by vascular endothelial growth factor (VEGF) acting via Src and by tumor necrosis factor-alpha acting via protein kinase C (PKC)bet... |
| 12-deoxyphorbolphenylacetate-20-acetate |
| 3-acetate9a-phenylacetate |
| 12-DPPAA |