Cdk4 Inhibitor (Cyclin-dependent kinase 4 Inhibitor)

Modify Date: 2025-08-25 17:10:27

Cdk4 Inhibitor (Cyclin-dependent kinase 4 Inhibitor) Structure
Cdk4 Inhibitor (Cyclin-dependent kinase 4 Inhibitor) structure
Common Name Cdk4 Inhibitor (Cyclin-dependent kinase 4 Inhibitor)
CAS Number 546102-60-7 Molecular Weight 404.21600
Density N/A Boiling Point N/A
Molecular Formula C20H10BrN3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Cdk4 Inhibitor (Cyclin-dependent kinase 4 Inhibitor)


Cdk4 inhibitor is a cell-permeable, asymmetrical indolocarbazole that exhibits antiproliferative activity by blocking cyclin D1/Cdk4 with an IC50 value of 0.8 μM.

 Names

Name Cdk4 Inhibitor
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C20H10BrN3O2
Molecular Weight 404.21600
Exact Mass 402.99600
PSA 81.24000
LogP 4.61210
InChIKey NMFKDDRQSNVETB-UHFFFAOYSA-N
SMILES O=C1NC(=O)c2c1c1c3ccccc3[nH]c1c1[nH]c3cc(Br)ccc3c21

 Synonyms

Indolocarbazole deriv. 4(d)
HMS3229E04
IN1380
2-Bromo-12,13-dihydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione
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