2-arachidonoylglycerol

Modify Date: 2024-01-03 17:17:04

2-arachidonoylglycerol Structure
2-arachidonoylglycerol structure
Common Name 2-arachidonoylglycerol
CAS Number 53847-30-6 Molecular Weight 378.545
Density 1.0±0.1 g/cm3 Boiling Point 508.6±50.0 °C at 760 mmHg
Molecular Formula C23H38O4 Melting Point N/A
MSDS USA Flash Point 163.0±23.6 °C
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger

 Use of 2-arachidonoylglycerol


2-Arachidonoylglycerol is a second endogenous cannabinoid ligand in the central nervous system.

 Names

Name 2-arachidonoylglycerol
Synonym More Synonyms

 2-arachidonoylglycerol Biological Activity

Description 2-Arachidonoylglycerol is a second endogenous cannabinoid ligand in the central nervous system.
Related Catalog
Target

Human Endogenous Metabolite

In Vitro 2-Arachidonylglycerol (2-AG) is a cannabinoid ligand isolated from intestinal tissue. 2-Arachidonoylglycerol activates neuronal cannabinoid receptors as a full agonist, and prevents the induction of long-term potentiation at CA3-CA1 synapses. 2-Arachidonoylglycerol binds to cannabinoid receptors and exerts several effects typical of cannabinoid drugs[1].
References

[1]. Stella N, et al. A second endogenous cannabinoid that modulates long-term potentiation. Nature. 1997 Aug 21;388(6644):773-8.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 508.6±50.0 °C at 760 mmHg
Molecular Formula C23H38O4
Molecular Weight 378.545
Flash Point 163.0±23.6 °C
Exact Mass 378.277008
PSA 66.76000
LogP 6.24
Vapour Pressure 0.0±3.0 mmHg at 25°C
Index of Refraction 1.508
Storage condition −20°C

 Safety Information

Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger
Hazard Statements H225-H302 + H312 + H332-H319
Precautionary Statements P210-P261-P280-P305 + P351 + P338-P370 + P378-P403 + P235
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xn: Harmful;F: Flammable;
Risk Phrases R11
Safety Phrases S26-S36/37
RIDADR UN 1648 3/PG 2
WGK Germany 2
HS Code 2916190090

 Precursor & DownStream

Precursor  0

DownStream  2

 Customs

HS Code 2916190090
Summary 2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%

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 Synonyms

1,3-Dihydroxy-2-propanyl (5Z,8Z,11Z,14Z)-5,8,11,14-icosatetraenoate
1,3-Dihydroxypropan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate
MFCD01862600
5,8,11,14-Eicosatetraenoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester, (5Z,8Z,11Z,14Z)-
2-arachidonoylglycerol
2-Arachidonyl Glycerol
EINECS 200-835-2
2-arachidonoyl glycerol