4-HYDROXYBENZALDEHYDE THIOSEMI-CARBAZONE

Modify Date: 2024-01-31 08:04:31

4-HYDROXYBENZALDEHYDE THIOSEMI-CARBAZONE Structure
4-HYDROXYBENZALDEHYDE THIOSEMI-CARBAZONE structure
Common Name 4-HYDROXYBENZALDEHYDE THIOSEMI-CARBAZONE
CAS Number 5339-74-2 Molecular Weight 195.24200
Density 1.467g/cm3 Boiling Point 351.2ºC at 760 mmHg
Molecular Formula C8H9N3OS Melting Point N/A
MSDS N/A Flash Point 166.2ºC

 Names

Name [(4-oxocyclohexa-2,5-dien-1-ylidene)methylamino]thiourea
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.467g/cm3
Boiling Point 351.2ºC at 760 mmHg
Molecular Formula C8H9N3OS
Molecular Weight 195.24200
Flash Point 166.2ºC
Exact Mass 195.04700
PSA 102.73000
LogP 1.65050
Index of Refraction 1.781

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CU6825000
CHEMICAL NAME :
Benzaldehyde, p-hydroxy-, thiosemicarbazone
CAS REGISTRY NUMBER :
5339-74-2
BEILSTEIN REFERENCE NO. :
2097419
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C8-H9-N3-O-S
MOLECULAR WEIGHT :
195.26
WISWESSER LINE NOTATION :
ZMYUS&MVR DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,37,1953
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 2,764,1950
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 6,52,1954
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
320 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#01021

 Safety Information

HS Code 2930909090

 Synthetic Route

~89%

4-HYDROXYBENZALDEHYDE THIOSEMI-CARBAZONE Structure

4-HYDROXYBENZAL...

CAS#:5339-74-2

Literature: Alam, Mohammad Sayed; Liu, Lijun; Lee, Yong-Eok; Lee, Dong-Ung Chemical and Pharmaceutical Bulletin, 2011 , vol. 59, # 5 p. 568 - 573 Title/Abstract Full Text View citing articles Show Details Alam, Mohammad Sayed; Liu, Lijun; Lee, Dong Ung Chemical and Pharmaceutical Bulletin, 2011 , vol. 59, # 11 p. 1413 - 1416

~77%

4-HYDROXYBENZALDEHYDE THIOSEMI-CARBAZONE Structure

4-HYDROXYBENZAL...

CAS#:5339-74-2

Literature: Rajak, Harish; Agarawal, Avantika; Parmar, Poonam; Thakur, Bhupendra Singh; Veerasamy, Ravichandran; Sharma, Prabodh Chander; Kharya, Murli Dhar Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 19 p. 5735 - 5738

~77%

4-HYDROXYBENZALDEHYDE THIOSEMI-CARBAZONE Structure

4-HYDROXYBENZAL...

CAS#:5339-74-2

Literature: Mahmoud Egyptian Journal of Chemistry, 2007 , vol. 50, # 3 p. 287 - 302

~%

4-HYDROXYBENZALDEHYDE THIOSEMI-CARBAZONE Structure

4-HYDROXYBENZAL...

CAS#:5339-74-2

Literature: Puetzer et al. Journal of the American Chemical Society, 1951 , vol. 73, p. 2958

 Customs

HS Code 2930909090
Summary 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

p-Hydroxybenzaldehyd-thiosemicarbazon
2-[(4-hydroxyphenyl)methylene]hydrazinecarbothioamine
p-Hydroxybenzaldehyde thiosemicarbazone
2-(4-hydroxybenzylidene)hydrazinecarbothioamide
EINECS 226-273-8
Semicarbazide,1-(p-hydroxybenzylidene)-3-thio
Benzaldehyde,p-hydroxy-,thiosemicarbazone
4-Hydroxy-benzaldehyd-thiosemicarbazon
1-(p-Hydroxybenzylidene)thiosemicarbazide
4-hydroxy-benzaldehyde thiosemicarbazone