5,7-Dihydroxy-6-(3-methyl-2-butenyl)-8-(3-methylbutyryl)-4-phenyl-2H-1-benzopyran-2-one
5,7-Dihydroxy-6-(3-methyl-2-butenyl)-8-(3-methylbutyryl)-4-phenyl-2H-1-benzopyran-2-one structure
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Common Name | 5,7-Dihydroxy-6-(3-methyl-2-butenyl)-8-(3-methylbutyryl)-4-phenyl-2H-1-benzopyran-2-one | ||
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| CAS Number | 5224-54-4 | Molecular Weight | 406.47100 | |
| Density | 1.219g/cm3 | Boiling Point | 629.1ºC at 760 mmHg | |
| Molecular Formula | C25H26O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 215.3ºC | |
Use of 5,7-Dihydroxy-6-(3-methyl-2-butenyl)-8-(3-methylbutyryl)-4-phenyl-2H-1-benzopyran-2-oneMammea A/BA has potent activity against Trypanosoma cruzi (T. cruzi). Mammea A/BA induces mitochondrial dysfunction, ROS production and DNA fragmentation, and increases number of acidic vacuoles. Mammea A/BA can induce apoptosis, autophagy and necrosis. Mammea A/BA can be used for researching chagas disease[1]. |
| Name | 5,7-dihydroxy-8-(3-methylbutanoyl)-6-(3-methylbut-2-enyl)-4-phenylchromen-2-one |
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| Synonym | More Synonyms |
| Description | Mammea A/BA has potent activity against Trypanosoma cruzi (T. cruzi). Mammea A/BA induces mitochondrial dysfunction, ROS production and DNA fragmentation, and increases number of acidic vacuoles. Mammea A/BA can induce apoptosis, autophagy and necrosis. Mammea A/BA can be used for researching chagas disease[1]. |
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| Related Catalog | |
| Target |
T. cruzi[1] |
| References |
| Density | 1.219g/cm3 |
|---|---|
| Boiling Point | 629.1ºC at 760 mmHg |
| Molecular Formula | C25H26O5 |
| Molecular Weight | 406.47100 |
| Flash Point | 215.3ºC |
| Exact Mass | 406.17800 |
| PSA | 87.74000 |
| LogP | 5.60870 |
| Index of Refraction | 1.607 |
| InChIKey | SBHOAZQBEGVQLJ-UHFFFAOYSA-N |
| SMILES | CC(C)=CCc1c(O)c(C(=O)CC(C)C)c2oc(=O)cc(-c3ccccc3)c2c1O |
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5,7-Dihydroxy-6... CAS#:5224-54-4 |
| Literature: Crombie; Jones; Palmer Tetrahedron Letters, 1985 , vol. 26, # 24 p. 2929 - 2932 |
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5,7-Dihydroxy-6... CAS#:5224-54-4 |
| Literature: Crombie, Leslie; Jones, Raymond C. F.; Palmer, Christopher J. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 317 - 332 |
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~%
5,7-Dihydroxy-6... CAS#:5224-54-4 |
| Literature: Crombie, Leslie; Jones, Raymond C. F.; Palmer, Christopher J. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 317 - 332 |
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~%
5,7-Dihydroxy-6... CAS#:5224-54-4 |
| Literature: Crombie, Leslie; Jones, Raymond C. F.; Palmer, Christopher J. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 317 - 332 |
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~22%
5,7-Dihydroxy-6... CAS#:5224-54-4 |
| Literature: Crombie, Leslie; Jones, Raymond C. F.; Palmer, Christopher J. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 317 - 332 |
|
~%
5,7-Dihydroxy-6... CAS#:5224-54-4 |
| Literature: Crombie, Leslie; Jones, Raymond C. F.; Palmer, Christopher J. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 317 - 332 |
|
~%
5,7-Dihydroxy-6... CAS#:5224-54-4 |
| Literature: Crombie, Leslie; Jones, Raymond C. F.; Palmer, Christopher J. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 317 - 332 |
| Mammea A/BA |
| isomammeisin |