1-[(3,4,5-Trimethoxyphenyl)methyl]piperazine

Modify Date: 2025-08-28 18:38:48

1-[(3,4,5-Trimethoxyphenyl)methyl]piperazine Structure
1-[(3,4,5-Trimethoxyphenyl)methyl]piperazine structure
Common Name 1-[(3,4,5-Trimethoxyphenyl)methyl]piperazine
CAS Number 52146-35-7 Molecular Weight 266.33600
Density 1.092g/cm3 Boiling Point 373.4ºC at 760mmHg
Molecular Formula C14H22N2O3 Melting Point 102-105 ºC
MSDS N/A Flash Point 179.6ºC

 Names

Name 1-(3,4,5-Trimethoxybenzyl)piperazine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.092g/cm3
Boiling Point 373.4ºC at 760mmHg
Melting Point 102-105 ºC
Molecular Formula C14H22N2O3
Molecular Weight 266.33600
Flash Point 179.6ºC
Exact Mass 266.16300
PSA 42.96000
LogP 1.38430
Index of Refraction 1.523
Water Solubility Freely soluble (140 g/L) (25 ºC)

 Safety Information

HS Code 2933599090

 Synthetic Route

~85%

1-[(3,4,5-Trimethoxyphenyl)methyl]piperazine Structure

1-[(3,4,5-Trime...

CAS#:52146-35-7

Literature: Zhang, Cunlong; Tan, Chunyan; Zu, Xuyu; Zhai, Xin; Liu, Feng; Chu, Bizhu; Ma, Xiaohua; Chen, Yuzong; Gong, Ping; Jiang, Yuyang European Journal of Medicinal Chemistry, 2011 , vol. 46, # 4 p. 1404 - 1414

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1-[(3,4,5-Trimethoxyphenyl)methyl]piperazine Structure

1-[(3,4,5-Trime...

CAS#:52146-35-7

Literature: Ferte, Jacques; Kuehnel, Jean-Marc; Chapuis, Genevieve; Rolland, Yves; Lewin, Guy; Schwaller, Marc A. Journal of Medicinal Chemistry, 1999 , vol. 42, # 3 p. 478 - 489

~%

1-[(3,4,5-Trimethoxyphenyl)methyl]piperazine Structure

1-[(3,4,5-Trime...

CAS#:52146-35-7

Literature: Ferte, Jacques; Kuehnel, Jean-Marc; Chapuis, Genevieve; Rolland, Yves; Lewin, Guy; Schwaller, Marc A. Journal of Medicinal Chemistry, 1999 , vol. 42, # 3 p. 478 - 489

 Customs

HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

1-(3,4,5-trimethoxy-benzyl)-piperazine
Trimetazidine Impurity A DiHCl
1-[(3,4,5-Trimethoxyphenyl)methyl]piperazine
Trimetazidine Impurity 1
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