Shikonin

Modify Date: 2024-01-01 22:45:44

Shikonin structure	Common Name	Shikonin
	CAS Number	517-88-4	Molecular Weight	288.295
	Density	1.4±0.1 g/cm3	Boiling Point	567.4±50.0 °C at 760 mmHg
	Molecular Formula	C₁₆H₁₆O₅	Melting Point	149°
	MSDS	USA	Flash Point	311.0±26.6 °C

Use of Shikonin

Alkannin, found in Alkanna tinctoria, is used as a food coloring. Alkannin shows anticancer activity, arrests cell cycle, and induces apoptosis. Alkannin improves hepatic inflammation in a Rho-kinase pathway[1][2][3].

Name	5,8-dihydroxy-2-[(1S)-1-hydroxy-4-methylpent-3-enyl]naphthalene-1,4-dione
Synonym	More Synonyms

Description	Alkannin, found in Alkanna tinctoria, is used as a food coloring. Alkannin shows anticancer activity, arrests cell cycle, and induces apoptosis. Alkannin improves hepatic inflammation in a Rho-kinase pathway[1][2][3].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Research Areas >> Inflammation/Immunology
In Vitro	Alkannin inhibits HCT-116 and SW-480 cells growth with IC50s of 2.38 and 4.53 µM, respectively[1].
References	[1]. Hosokawa Y, et al. Alkannin inhibits CCL3 and CCL5 production in human periodontal ligament cells. Cell Biol Int. 2016 Dec;40(12):1380-1385. [2]. Huu Tung N, et al. Naphthoquinone components from Alkanna tinctoria (L.) Tausch show significant antiproliferative effects on human colorectal cancer cells. Phytother Res. 2013 Jan;27(1):66-70. [3]. Xue W, et al. Alkannin Inhibited Hepatic Inflammation in Diabetic Db/Db Mice. Cell Physiol Biochem. 2018;45(6):2461-2470.

Density	1.4±0.1 g/cm3
Boiling Point	567.4±50.0 °C at 760 mmHg
Melting Point	149°
Molecular Formula	C₁₆H₁₆O₅
Molecular Weight	288.295
Flash Point	311.0±26.6 °C
Exact Mass	288.099762
PSA	94.83000
LogP	4.35
Vapour Pressure	0.0±1.6 mmHg at 25°C
Index of Refraction	1.642

Shikonin MSDS(Chinese)

RIDADR	NONH for all modes of transport

Precursor 0
DownStream 4
CAS#:3724-65-0 Crotonic acid CAS#:84273-03-0 Shikonin Crotonate CAS#:76549-35-4 Isovalerylshikonin CAS#:84272-99-1 [1-(5,8-dihydro...

Integrative analysis of 111 reference human epigenomes.

Nature 518(7539) , 317-30, (2015)

The reference human genome sequence set the stage for studies of genetic variation and its association with human disease, but epigenomic studies lack a similar reference. To address this need, the NI...

Alkannin (VAN)

5,8-dihydroxy-2-[(1S)-1-hydroxy-4-methylpent-3-en-1-yl]naphthalene-1,4-dione

5,8-Dihydroxy-2-[(1S)-1-hydroxy-4-methylpent-3-en-1-yl]-1,4-naphthoquinone

Anchusa acid (VAN)

Anchusin (VAN)

C.I. Natural Red 20

(S)-5,8-Dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-1,4-naphthalenedione

1,4-Naphthalenedione, 5,8-dihydroxy-2-[(1S)-1-hydroxy-4-methyl-3-penten-1-yl]-

Alkanna red (VAN)

Alkannin

Anchusa acid

Anchusin

(-)-5,8-Dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-1,4-naphthoquinone

Alkanna Red

5,8-Dihydroxy-2-[(1S)-1-hydroxy-4-methyl-3-penten-1-yl]-1,4-naphthoquinone

C.I. Natural Red 20 (VAN)

EINECS 208-245-7

(1-Hydroxy-3-isohexenyl)naphthazarine

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Shikonin
Price: ￥448.0/20mg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

DC Chemicals Limited
China
Product Name: (-)-Alkannin
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Alkannin
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

Get all suppliers and price by the below link:

Shikonin suppliers

Shikonin price

Shikonin

Use of Shikonin

Names

Shikonin Biological Activity

Chemical & Physical Properties

MSDS

Safety Information

Precursor & DownStream

Articles1

Synonyms