CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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DW4000000
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CHEMICAL NAME :
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(4,4'-Bi-3-pyrazoline)-5,5'-dione, 1,1'-diphenyl-2,2',3,3'-tetramethyl-
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CAS REGISTRY NUMBER :
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517-83-9
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BEILSTEIN REFERENCE NO. :
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0351034
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LAST UPDATED :
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199612
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DATA ITEMS CITED :
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2
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MOLECULAR FORMULA :
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C22-H22-N4-O2
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MOLECULAR WEIGHT :
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374.48
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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5 mg/kg
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TOXIC EFFECTS :
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Behavioral - convulsions or effect on seizure threshold
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REFERENCE :
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85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2 vols., Ann Arbor, MI, J.W. Edwards, 1946 Volume(issue)/page/year: 1,233,1946 ** OTHER MULTIPLE DOSE TOXICITY DATA **
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Mammal - dog
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DOSE/DURATION :
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15 gm/kg/22W-I
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TOXIC EFFECTS :
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Behavioral - ataxia Blood - normocytic anemia Related to Chronic Data - death
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REFERENCE :
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85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2 vols., Ann Arbor, MI, J.W. Edwards, 1946 Volume(issue)/page/year: 1,233,1946
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