CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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NX8155650
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CHEMICAL NAME :
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4-Isothiazolecarboxamide, 5-(benzoylamino)-N-(p-chlorophenyl)-3-methyl-
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CAS REGISTRY NUMBER :
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51287-57-1
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LAST UPDATED :
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199406
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DATA ITEMS CITED :
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4
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MOLECULAR FORMULA :
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C18-H14-Cl-N3-O2-S
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MOLECULAR WEIGHT :
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371.86
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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>3 gm/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.10- 1962- Volume(issue)/page/year: 28,393,1980
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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330 mg/kg
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TOXIC EFFECTS :
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Behavioral - changes in motor activity (specific assay) Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation
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REFERENCE :
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AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.10- 1962- Volume(issue)/page/year: 28,393,1980
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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>3 gm/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
-
AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.10- 1962- Volume(issue)/page/year: 28,393,1980
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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219 mg/kg
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TOXIC EFFECTS :
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Behavioral - changes in motor activity (specific assay) Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation
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REFERENCE :
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AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.10- 1962- Volume(issue)/page/year: 28,393,1980
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