D77
Modify Date: 2024-01-29 05:11:32
D77 structure
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Common Name | D77 | ||
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| CAS Number | 497836-10-9 | Molecular Weight | 596.45 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H22BrNO7S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of D77D77 is anti-HIV-1 inhibitor targeting the interaction between integrase and cellular LEDGF/p75. D77 inhibits HIV-1(IIIB) replication by EC50 value of 23.8 μg/ml in MT-4 cell (5.03 μg/ml for C8166 cells).IC50 value: 23.8 μg/ml (EC50, in MT-4 cell ), 5.03 μg/ml (EC50, in C8166 cell)Target: HIV-1in vitro: D77 exhibits a highly specific binding affinity to HIV-1 integrase catalytic core domain.D77 induces a dramatic concentration-dependent decrease of α-galactosidase activity compared to the D77-untreated cells. D77 reveals a significant inhibition activity against the interaction of IN with IBD. |
| Name | D77 |
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| Description | D77 is anti-HIV-1 inhibitor targeting the interaction between integrase and cellular LEDGF/p75. D77 inhibits HIV-1(IIIB) replication by EC50 value of 23.8 μg/ml in MT-4 cell (5.03 μg/ml for C8166 cells).IC50 value: 23.8 μg/ml (EC50, in MT-4 cell ), 5.03 μg/ml (EC50, in C8166 cell)Target: HIV-1in vitro: D77 exhibits a highly specific binding affinity to HIV-1 integrase catalytic core domain.D77 induces a dramatic concentration-dependent decrease of α-galactosidase activity compared to the D77-untreated cells. D77 reveals a significant inhibition activity against the interaction of IN with IBD. |
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| Related Catalog | |
| References |
| Molecular Formula | C28H22BrNO7S |
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| Molecular Weight | 596.45 |
| Storage condition | 2-8℃ |