HhAntag

Modify Date: 2025-08-21 12:56:07

HhAntag structure	Common Name	HhAntag
	CAS Number	496794-70-8	Molecular Weight	450.91700
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₂₃ClN₄O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of HhAntag

HhAntag is a small molecule inhibitor of GLI1-mediated transcription, an essential down-stream element of the Hedgehog (Hh) pathway; antitumor agent.IC50 value:Target: Gli

Name	N-[4-chloro-3-[6-(dimethylamino)-1H-benzimidazol-2-yl]phenyl]-3,5-dimethoxybenzamide
Synonym	More Synonyms

Description	HhAntag is a small molecule inhibitor of GLI1-mediated transcription, an essential down-stream element of the Hedgehog (Hh) pathway; antitumor agent.IC50 value:Target: Gli
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> Gli Research Areas >> Cancer
References	[1]. Actis, Marcelo; Connelly, Michele C.; Mayasundari, Anand et al. A structure-activity relationship study of small-molecule inhibitors of GLI1-mediated transcription. Biopolymers (2011), 95(1), 24-30. [2]. Mahindroo, Neeraj; Connelly, Michele C.; Punchihewa, Chandanamali; et al. Amide conjugates of ketoprofen and indole as inhibitors of Gli1-mediated transcription in the Hedgehog pathway. Bioorganic & Medicinal Chemistry (2010), 18(13), 4801-4811. [3]. Yauch, Robert L.; Gould, Stephen E.; Scales, Suzie J.; et al. A paracrine requirement for hedgehog signalling in cancer. Nature (London, United Kingdom) (2008), 455(7211), 406-410.

Description

HhAntag is a small molecule inhibitor of GLI1-mediated transcription, an essential down-stream element of the Hedgehog (Hh) pathway; antitumor agent.IC50 value:Target: Gli

Related Catalog

Signaling Pathways >> Stem Cell/Wnt >> Gli

Research Areas >> Cancer

References

[1]. Actis, Marcelo; Connelly, Michele C.; Mayasundari, Anand et al. A structure-activity relationship study of small-molecule inhibitors of GLI1-mediated transcription. Biopolymers (2011), 95(1), 24-30.

[2]. Mahindroo, Neeraj; Connelly, Michele C.; Punchihewa, Chandanamali; et al. Amide conjugates of ketoprofen and indole as inhibitors of Gli1-mediated transcription in the Hedgehog pathway. Bioorganic & Medicinal Chemistry (2010), 18(13), 4801-4811.

[3]. Yauch, Robert L.; Gould, Stephen E.; Scales, Suzie J.; et al. A paracrine requirement for hedgehog signalling in cancer. Nature (London, United Kingdom) (2008), 455(7211), 406-410.

Molecular Formula	C₂₄H₂₃ClN₄O₃
Molecular Weight	450.91700
Exact Mass	450.14600
PSA	82.97000
LogP	5.60280
Storage condition	2-8℃

CS-1233

GLI1-mediated tranion inhibitor

HhAntag

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: HhAntag
Price: Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: HhAntag
Price: $550.0/100mg $1000.0/250mg $1900.0/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: HhAntag
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

Get all suppliers and price by the below link:

HhAntag suppliers

Price: $325/10mM*1mLinDMSO

Reference only. check more HhAntag price

HhAntag

Use of HhAntag

Names

HhAntag Biological Activity

Chemical & Physical Properties

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.