5-Ethyl-4-(4-methoxyphenyl)-1,3-thiazol-2-amine

Modify Date: 2024-01-03 11:18:50

5-Ethyl-4-(4-methoxyphenyl)-1,3-thiazol-2-amine Structure
5-Ethyl-4-(4-methoxyphenyl)-1,3-thiazol-2-amine structure
Common Name 5-Ethyl-4-(4-methoxyphenyl)-1,3-thiazol-2-amine
CAS Number 493028-20-9 Molecular Weight 234.317
Density 1.2±0.1 g/cm3 Boiling Point 421.5±40.0 °C at 760 mmHg
Molecular Formula C12H14N2OS Melting Point N/A
MSDS N/A Flash Point 208.7±27.3 °C

 Use of 5-Ethyl-4-(4-methoxyphenyl)-1,3-thiazol-2-amine


Runx1-CBFβ interaction inhibitor 1 is an allosteric inhibitior of Runt domain-CBFb interaction (IC50=3.2 μM)[1].

 Names

Name 5-ethyl-4-(4-methoxyphenyl)-1,3-thiazol-2-amine
Synonym More Synonyms

  Biological Activity

Description Runx1-CBFβ interaction inhibitor 1 is an allosteric inhibitior of Runt domain-CBFb interaction (IC50=3.2 μM)[1].
Related Catalog
References

[1]. Michael J Gorczynski, et al. Allosteric inhibition of the protein-protein interaction between the leukemia-associated proteins Runx1 and CBFbeta. Chem Biol. 2007 Oct;14(10):1186-97.  

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 421.5±40.0 °C at 760 mmHg
Molecular Formula C12H14N2OS
Molecular Weight 234.317
Flash Point 208.7±27.3 °C
Exact Mass 234.082687
PSA 76.38000
LogP 2.94
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.606

 Safety Information

HS Code 2934100090

 Customs

HS Code 2934100090
Summary 2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

 Synonyms

2-Thiazolamine, 5-ethyl-4-(4-methoxyphenyl)-
5-Ethyl-4-(4-methoxyphenyl)-1,3-thiazol-2-amine
thiazol-2-amine,17