Phthiocol

Modify Date: 2024-01-03 17:35:09

Phthiocol Structure
Phthiocol structure
Common Name Phthiocol
CAS Number 483-55-6 Molecular Weight 188.17900
Density 1.389 g/cm3 Boiling Point 342.655ºC at 760 mmHg
Molecular Formula C11H8O3 Melting Point N/A
MSDS N/A Flash Point 175.232ºC

 Names

Name 4-hydroxy-3-methylnaphthalene-1,2-dione
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.389 g/cm3
Boiling Point 342.655ºC at 760 mmHg
Molecular Formula C11H8O3
Molecular Weight 188.17900
Flash Point 175.232ºC
Exact Mass 188.04700
PSA 54.37000
LogP 1.89760
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.646

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QL8485000
CHEMICAL NAME :
1,4-Naphthoquinone, 2-hydroxy-3-methyl-
CAS REGISTRY NUMBER :
483-55-6
BEILSTEIN REFERENCE NO. :
1868473
LAST UPDATED :
199709
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C11-H8-O3
MOLECULAR WEIGHT :
188.19
WISWESSER LINE NOTATION :
L66 BV EVJ CQ D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Bird - chicken
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3 gm/kg/30D-I
TOXIC EFFECTS :
Blood - pigmented or nucleated red blood cells Blood - changes in erythrocyte (RBC) count

MUTATION DATA

TYPE OF TEST :
DNA inhibition
TEST SYSTEM :
Human HeLa cell
DOSE/DURATION :
4 mmol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 93,447,1982

 Synthetic Route

 Synonyms

1,4-Naphthalenedione,2-hydroxy-3-methyl
2-hydroxy-3-methyl-1,4-naphthalenedione
Phthiokol
3-Hydroxy-2-methyl-1,4-naphthoquinone
Phthiocol
EINECS 207-594-2
2-Methyl-3-hydroxy-1,4-naphthoquinone
1,4-Naphthoquinone,2-hydroxy-3-methyl
2-Hydroxy-3-methyl-1,4-naphthoquinone
2-hydroxy-3-methylnaphthalene-1,4-dione
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