R1487 Hydrochloride
Modify Date: 2025-08-29 19:12:11
R1487 Hydrochloride structure
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Common Name | R1487 Hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 449808-64-4 | Molecular Weight | 424.829 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H19ClF2N4O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of R1487 HydrochlorideR1487 (Hydrochloride) is highly potent and highly selective inhibitors of p38α.target: p38α;R1487 (Hydrochloride) potently inhibits cytokine production in a variety of in vitro and in vivo models.[1]R1487 (Hydrochloride) inhibits production of TNFR by human monocytic cells (THP-1) and inhibits production of IL-1β in human whole blood (HWB) induced by LPS.[1] |
| Name | R1487 HCl |
|---|---|
| Synonym | More Synonyms |
| Description | R1487 (Hydrochloride) is highly potent and highly selective inhibitors of p38α.target: p38α;R1487 (Hydrochloride) potently inhibits cytokine production in a variety of in vitro and in vivo models.[1]R1487 (Hydrochloride) inhibits production of TNFR by human monocytic cells (THP-1) and inhibits production of IL-1β in human whole blood (HWB) induced by LPS.[1] |
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| Related Catalog | |
| References |
| Molecular Formula | C19H19ClF2N4O3 |
|---|---|
| Molecular Weight | 424.829 |
| Exact Mass | 424.111389 |
| PSA | 81.50000 |
| LogP | 3.21380 |
| InChIKey | RQHSAIGGUWVOBG-UHFFFAOYSA-N |
| SMILES | Cl.Cn1c(=O)c(Oc2ccc(F)cc2F)cc2cnc(NC3CCOCC3)nc21 |
| Storage condition | 2-8℃ |
| 6-(2,4-Difluorophenoxy)-8-methyl-2-(tetrahydro-2H-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one hydrochloride (1:1) |
| R-1487 Hydrochloride |
| Pyrido[2,3-d]pyrimidin-7(8H)-one,6-(2,4-difluorophenoxy)-8-methyl-2-[(tetrahydro-2H-pyran-4-yl)amino]-,hydrochloride |
| 6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one hydrochloride |
| Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-(2,4-difluorophenoxy)-8-methyl-2-[(tetrahydro-2H-pyran-4-yl)amino]-, hydrochloride (1:1) |
| QC-6149 |
| RS0052 |
| R1487 Hydrochloride |