Norwogonin

Modify Date: 2024-01-08 14:13:20

Norwogonin structure	Common Name	Norwogonin
	CAS Number	4443-09-8	Molecular Weight	270.23700
	Density	1.548g/cm3	Boiling Point	528.4ºC at 760 mmHg
	Molecular Formula	C₁₅H₁₀O₅	Melting Point	258 ºC (ethanol )
	MSDS	N/A	Flash Point	206ºC

Use of Norwogonin

Norwogonin, isolated from Scutellaria baicalensis Georgi, possesses antiviral activity against Enterovirus 71 (EV71) with an IC50 of 31.83 μg/ml[1]

Name	norwogonin
Synonym	More Synonyms

Description	Norwogonin, isolated from Scutellaria baicalensis Georgi, possesses antiviral activity against Enterovirus 71 (EV71) with an IC50 of 31.83 μg/ml[1]
Related Catalog	Research Areas >> Infection
Target	IC50: 31.83 μg/ml (EV71)[1]
In Vitro	Norwogonin (0.4, 2, 10, and 50 μg/mL; 48 hours) inhibits EV71 replication in Vero cells and prevents the cytotoxicity induced by EV71 infection[1]. Norwogonin (50 μg/mL; 48 hours) dramatically decreases viral VP2 protein expression[1]. Norwogonin (50 μg/mL; 48 hours) strongly decreases the expression of EV71 NCR gene at 48 h[1].
References	[1]. Choi HJ, et al. Inhibitory Effects of Norwogonin, Oroxylin A, and Mosloflavone on Enterovirus 71. Biomol Ther (Seoul). 2016 Sep 1;24(5):552-8.

Density	1.548g/cm3
Boiling Point	528.4ºC at 760 mmHg
Melting Point	258 ºC (ethanol )
Molecular Formula	C₁₅H₁₀O₅
Molecular Weight	270.23700
Flash Point	206ºC
Exact Mass	270.05300
PSA	90.90000
LogP	2.57680
Index of Refraction	1.732
Storage condition	2-8°C
Water Solubility	Very slightly soluble (0.26 g/L) (25 ºC)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LK9276100

CHEMICAL NAME :: Flavone, 5,7,8-trihydroxy-

CAS REGISTRY NUMBER :: 4443-09-8

BEILSTEIN REFERENCE NO. :: 0272168

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C15-H10-O5

MOLECULAR WEIGHT :: 270.25

WISWESSER LINE NOTATION :: T66 BO EVJ CR& GQ IQ JQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 1 nmol/plate

REFERENCE :: ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 5,474,1983

HS Code	2914400090

HS Code	2914400090
Summary	2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Norwogonin

5,7,8-Trihydroxyflavone

5,7,8-trihydroxy-2-phenyl-chromen-4-one

FLAVONE,5,7,8-TRIHYDROXY

2-Phenyl-5,7,8-trihydroxy-4H-1-benzopyran-4-one

5,7,8-trihydroxy-2-phenylchromen-4-one

5,7,8-Trihydroxy-2-phenyl-chromen-4-on

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Norwogonin
Price: ￥4418.0/5mg
Purity: 98.0%
Stocking Period: 2 Day
Contact: Liu jia

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Norwogonin

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