m-PEG7-alcohol

Modify Date: 2024-01-03 17:11:05

m-PEG7-alcohol Structure
m-PEG7-alcohol structure
Common Name m-PEG7-alcohol
CAS Number 4437-01-8 Molecular Weight 340.410
Density 1.1±0.1 g/cm3 Boiling Point 416.0±40.0 °C at 760 mmHg
Molecular Formula C15H32O8 Melting Point N/A
MSDS N/A Flash Point 205.4±27.3 °C

 Use of m-PEG7-alcohol


m-PEG7-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2,5,8,11,14,17,20-Heptaoxadocosan-22-ol
Synonym More Synonyms

 m-PEG7-alcohol Biological Activity

Description m-PEG7-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 416.0±40.0 °C at 760 mmHg
Molecular Formula C15H32O8
Molecular Weight 340.410
Flash Point 205.4±27.3 °C
Exact Mass 340.209717
PSA 84.84000
LogP -2.95
Vapour Pressure 0.0±2.2 mmHg at 25°C
Index of Refraction 1.449

 Safety Information

WGK Germany 3
HS Code 2909499000

 Synthetic Route

 Customs

HS Code 2909499000
Summary 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

 Synonyms

2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
MFCD06201006
Heptaethylene Glycol MonoMethyl Ether
2,5,8,11,14,17,20-Heptaoxadocosan-22-ol
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