Benzenesulfonamide,N,N'-1,2-ethanediylbis[4-methyl-

Modify Date: 2025-08-24 18:17:14

Benzenesulfonamide,N,N'-1,2-ethanediylbis[4-methyl- Structure
Benzenesulfonamide,N,N'-1,2-ethanediylbis[4-methyl- structure
Common Name Benzenesulfonamide,N,N'-1,2-ethanediylbis[4-methyl-
CAS Number 4403-78-5 Molecular Weight 368.47100
Density 1.297g/cm3 Boiling Point 549.9ºC at 760 mmHg
Molecular Formula C16H20N2O4S2 Melting Point N/A
MSDS N/A Flash Point 286.4ºC

 Names

Name 4-methyl-N-[2-[(4-methylphenyl)sulfonylamino]ethyl]benzenesulfonamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.297g/cm3
Boiling Point 549.9ºC at 760 mmHg
Molecular Formula C16H20N2O4S2
Molecular Weight 368.47100
Flash Point 286.4ºC
Exact Mass 368.08600
PSA 109.10000
LogP 4.50360
Index of Refraction 1.582
InChIKey HOFGETLODCEHBQ-UHFFFAOYSA-N
SMILES Cc1ccc(S(=O)(=O)NCCNS(=O)(=O)c2ccc(C)cc2)cc1

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XT5748000
CHEMICAL NAME :
p-Toluenesulfonamide, N,N'-ethylenebis-
CAS REGISTRY NUMBER :
4403-78-5
BEILSTEIN REFERENCE NO. :
2399549
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C16-H20-N2-O4-S2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,41,1953

 Safety Information

HS Code 2935009090

 Synthetic Route

~99%

Benzenesulfonamide,N,N'-1,2-ethanediylbis[4-methyl- Structure

Benzenesulfonam...

CAS#:4403-78-5

Literature: Fukudome, Yasuhiro; Naito, Hiroyuki; Hata, Takeshi; Urabe, Hirokazu Journal of the American Chemical Society, 2008 , vol. 130, # 6 p. 1820 - 1821

~%

Benzenesulfonamide,N,N'-1,2-ethanediylbis[4-methyl- Structure

Benzenesulfonam...

CAS#:4403-78-5

Literature: Iwata, Masaaki; Kuzuhara, Hiroyoshi Bulletin of the Chemical Society of Japan, 1985 , vol. 58, # 11 p. 3395 - 3396

~78%

Benzenesulfonamide,N,N'-1,2-ethanediylbis[4-methyl- Structure

Benzenesulfonam...

CAS#:4403-78-5

Literature: Mizhiritskii, M. D.; Reikhsfel'd, V. O. J. Gen. Chem. USSR (Engl. Transl.), 1986 , vol. 56, # 7 p. 1547 - 1558,1373 - 1382

~%

Benzenesulfonamide,N,N'-1,2-ethanediylbis[4-methyl- Structure

Benzenesulfonam...

CAS#:4403-78-5

Literature: Howard; Marckwald Chemische Berichte, 1899 , vol. 32, p. 2035

~%

Detail
Literature: Barrett, Anthony G. M.; Lana, J. Carlos A.; Tograie, Shahrzad Journal of the Chemical Society, Chemical Communications, 1980 , # 7 p. 300 - 301

~%

Benzenesulfonamide,N,N'-1,2-ethanediylbis[4-methyl- Structure

Benzenesulfonam...

CAS#:4403-78-5

Literature: Peacock; Dutta Journal of the Chemical Society, 1934 , p. 1303

~%

Benzenesulfonamide,N,N'-1,2-ethanediylbis[4-methyl- Structure

Benzenesulfonam...

CAS#:4403-78-5

Detail
Literature: Hill, Roger R.; Jeffs, Graham E.; Roberts, David R.; Wood, Sharon A. Chemical Communications, 1999 , # 17 p. 1735 - 1736

 Customs

HS Code 2935009090
Summary 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

 Synonyms

4-methyl-N-(2-{[(4-methylphenyl)sulfonyl]amino}ethyl)benzenesulfonamide
N,N'-Bis(toluenesulfonyl)-1,2-ethylenediamine
N,N'-bis[(4-methylphenyl)sulfonyl]-1,2-ethylenediamine
p-Toluenesulfonamide,N,N'-ethylenebis
N,N'-di(p-toluenesulfonyl)ethylenediamine
1,4-bis-(p-toluenesulfonyl)-1,4-diazabutane
N,N'-Ethylenedi-p-toluenesulfonamide
N,N'-Ditosylethylenediamine
N,N'-ethylenedi(toluenesulfonamide)
N,N'-(ethane-1,2-diyl)bis(4-methyldibenzenesulfonamide)
N,N'-ethane-1,2-diylbis(4-methylbenzenesulfonamide)
N,N'-Ethylenebis-p-toluenesulfonamide
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