Dabigatran (ethyl ester)
Modify Date: 2025-10-25 20:43:59
Dabigatran (ethyl ester) structure
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Common Name | Dabigatran (ethyl ester) | ||
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| CAS Number | 429658-95-7 | Molecular Weight | 499.564 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 759.5±70.0 °C at 760 mmHg | |
| Molecular Formula | C27H29N7O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 413.1±35.7 °C | |
Use of Dabigatran (ethyl ester)ethyl ester of Dabigatran, which is an emerging oral anticoagulant which is a direct inhibitor of thrombin activity. IC50 value:Target: thrombinDabigatran provides a stable anticoagulation effect without any need to perform periodical laboratory controls. Of note, there is a growing amount of clinical evidence which shows its safety and efficacy. For these reasons, Dabigatran may suppose a revolution in oral anticoagulation. Dabigatran etexilate was rapidly converted to Dabigatran, with peak plasma dabigatran concentrations being attained after approximately 1.5 h; the bioavailability of Dabigatran after p.o. administration of Dabigatran etexilate was 7.2%. |
| Name | ethyl 3-[[2-[(4-carbamimidoylanilino)methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoate |
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| Synonym | More Synonyms |
| Description | ethyl ester of Dabigatran, which is an emerging oral anticoagulant which is a direct inhibitor of thrombin activity. IC50 value:Target: thrombinDabigatran provides a stable anticoagulation effect without any need to perform periodical laboratory controls. Of note, there is a growing amount of clinical evidence which shows its safety and efficacy. For these reasons, Dabigatran may suppose a revolution in oral anticoagulation. Dabigatran etexilate was rapidly converted to Dabigatran, with peak plasma dabigatran concentrations being attained after approximately 1.5 h; the bioavailability of Dabigatran after p.o. administration of Dabigatran etexilate was 7.2%. |
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| Related Catalog | |
| References |
[5]. Dabigatran |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 759.5±70.0 °C at 760 mmHg |
| Molecular Formula | C27H29N7O3 |
| Molecular Weight | 499.564 |
| Flash Point | 413.1±35.7 °C |
| Exact Mass | 499.233185 |
| PSA | 139.22000 |
| LogP | 1.78 |
| Vapour Pressure | 0.0±2.6 mmHg at 25°C |
| Index of Refraction | 1.658 |
| InChIKey | BGLLICFSSKPUMR-UHFFFAOYSA-N |
| SMILES | CCOC(=O)CCN(C(=O)c1ccc2c(c1)nc(CNc1ccc(C(=N)N)cc1)n2C)c1ccccn1 |
| Storage condition | 2-8℃ |
| Ethyl N-[(2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-benzimidazol-5-yl)carbonyl]-N-2-pyridinyl-β-alaninate |
| Dabigatran ethyl AcOH Salt |
| Ethyl 3-(2-(((4-carbamimidoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate |
| C24 |
| 3-({2-[(4-CARBAMIMIDOYL-PHENYLAMINO)-METHYL]-3-METHYL-3H-BENZOIMIDAZOLE-5-CARBONYL}-PYRIDIN-2-YL-AMINO)-PROPIONIC ACID ETHYL ESTER |
| β-Alanine, N-[[2-[[[4-(aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-, ethyl ester |
| N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-beta-alanine ethyl ester |
| Dabigatran ethyl ester |
| Dabigatran (ethyl ester) |