Methyl 2-chloro-6-methoxyisonicotinate

Modify Date: 2024-01-14 17:32:33

Methyl 2-chloro-6-methoxyisonicotinate Structure
Methyl 2-chloro-6-methoxyisonicotinate structure
Common Name Methyl 2-chloro-6-methoxyisonicotinate
CAS Number 42521-10-8 Molecular Weight 201.607
Density 1.3±0.1 g/cm3 Boiling Point 281.6±35.0 °C at 760 mmHg
Molecular Formula C8H8ClNO3 Melting Point 97.5ºC
MSDS N/A Flash Point 124.1±25.9 °C

 Names

Name methyl 2-chloro-6-methoxypyridine-4-carboxylate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 281.6±35.0 °C at 760 mmHg
Melting Point 97.5ºC
Molecular Formula C8H8ClNO3
Molecular Weight 201.607
Flash Point 124.1±25.9 °C
Exact Mass 201.019272
PSA 48.42000
LogP 2.42
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.521

 Safety Information

HS Code 2933399090

 Synthetic Route

~84%

Methyl 2-chloro-6-methoxyisonicotinate Structure

Methyl 2-chloro...

CAS#:42521-10-8

Literature: AstraZeneca AB; NPS PHARMACEUTICALS, INC. Patent: US2007/259923 A1, 2007 ; Location in patent: Page/Page column 11 ; US 20070259923 A1

~79%

Methyl 2-chloro-6-methoxyisonicotinate Structure

Methyl 2-chloro...

CAS#:42521-10-8

Literature: MERCK SHARP and DOHME CORP.; STAMFORD, Andrew, W.; GILBERT, Eric, J.; CUMMING, Jared, N. Patent: WO2012/138590 A1, 2012 ; Location in patent: Page/Page column 72 ; WO 2012/138590 A1

~93%

Methyl 2-chloro-6-methoxyisonicotinate Structure

Methyl 2-chloro...

CAS#:42521-10-8

Literature: The Dow Chemical Company Patent: US4474602 A1, 1984 ;

~%

Methyl 2-chloro-6-methoxyisonicotinate Structure

Methyl 2-chloro...

CAS#:42521-10-8

Literature: Actelion Pharmaceuticals Ltd. Patent: US2010/63108 A1, 2010 ; Location in patent: Page/Page column 19 ; US 20100063108 A1

~%

Methyl 2-chloro-6-methoxyisonicotinate Structure

Methyl 2-chloro...

CAS#:42521-10-8

Literature: ACTELION PHARMACEUTICALS LTD; BOLLI, Martin; LESCOP, Cyrille; MATHYS, Boris; MORRISON, Keith; MUELLER, Claus; NAYLER, Oliver; STEINER, Beat Patent: WO2012/98505 A1, 2012 ; Location in patent: Page/Page column 27 ; WO 2012/098505 A1

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Methyl 2-chloro-6-methoxyisonicotinate Structure

Methyl 2-chloro...

CAS#:42521-10-8

Literature: BOEHRINGER INGELHEIM INTERNATIONAL GMBH; COOK, Brian Nicholas; DISALVO, Darren; FANDRICK, Daniel Robert; HARCKEN, Christian; KUZMICH, Daniel; LEE, Thomas Wai-Ho; LIU, Pingrong; LORD, John; MAO, Can; NEU, Jochen; RAUDENBUSH, Brian Christopher; RAZAVI, Hossein; REEVES, Jonathan Timothy; SONG, Jinhua, J.; SWINAMER, Alan, David; TAN, Zhulin Patent: WO2010/36632 A1, 2010 ; Location in patent: Page/Page column 176; 177 ;

~%

Methyl 2-chloro-6-methoxyisonicotinate Structure

Methyl 2-chloro...

CAS#:42521-10-8

Literature: ACTELION PHARMACEUTICALS LTD; BOLLI, Martin; LESCOP, Cyrille; MATHYS, Boris; MORRISON, Keith; MUELLER, Claus; NAYLER, Oliver; STEINER, Beat Patent: WO2012/98505 A1, 2012 ; WO 2012/098505 A1

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

4-Pyridinecarboxylic acid, 2-chloro-6-methoxy-, methyl ester
Methyl 2-chloro-6-methoxyisonicotinate
methyl (2-chloro-6-methoxypyridin-4-yl)carboxylate
2-Chlor-6-methoxy-isonicotinsaeure-methylester
methylchloromethoxyisonicotinate
2-chloro-6-methoxy-isonicotinic acid methyl ester
CL0091
methyl-2-methoxy-6-chloroisonicotinate
2-Chloro-6-methoxy-4-(methoxycarbonyl)pyridine