N-METHYL-2-PHTHALIMIDOGLUTARIMIDE

Modify Date: 2025-09-16 16:45:30

N-METHYL-2-PHTHALIMIDOGLUTARIMIDE structure	Common Name	N-METHYL-2-PHTHALIMIDOGLUTARIMIDE
	CAS Number	42472-93-5	Molecular Weight	272.25600
	Density	1.457g/cm3	Boiling Point	477ºC at 760 mmHg
	Molecular Formula	C₁₄H₁₂N₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	232ºC

Name	2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
Synonym	More Synonyms

Density	1.457g/cm3
Boiling Point	477ºC at 760 mmHg
Molecular Formula	C₁₄H₁₂N₂O₄
Molecular Weight	272.25600
Flash Point	232ºC
Exact Mass	272.08000
PSA	74.76000
LogP	0.30580
Index of Refraction	1.64

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MA5300000

CHEMICAL NAME :: Glutarimide, N-methyl-2-phthalimido-

CAS REGISTRY NUMBER :: 42472-93-5

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C14-H12-N2-O4

MOLECULAR WEIGHT :: 272.28

WISWESSER LINE NOTATION :: T56 BVNVJ C- DT6VNVTJ B1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 670 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: LIFSAK Life Sciences. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1-8, 1962-69; V.14- 1974- Volume(issue)/page/year: 3,721,1964 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 650 mg/kg

SEX/DURATION :: female 4-16 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - body wall Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Specific Developmental Abnormalities - other developmental abnormalities

REFERENCE :: LIFSAK Life Sciences. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1-8, 1962-69; V.14- 1974- Volume(issue)/page/year: 3,721,1964

methylamine

CAS#:74-89-5

N-Phthalyl-DL-g...

CAS#:3343-28-0

~68%

N-METHYL-2-PHTH...

CAS#:42472-93-5

Literature: Goosen; Laing; Plessis; Flynn Pharmaceutical Research, 2002 , vol. 19, # 1 p. 13 - 19

Precursor 2
CAS#:74-89-5 methylamine CAS#:3343-28-0 N-Phthalyl-DL-g...
DownStream 0

6-Methyl-2-phthalimido-glutarimid

methyl-thalidomide

Glutarimide,N-methyl-2-phthalimido

N-methyl thalidomide

2-Phthalimido-N-methyl-glutarimide

2-(1-methyl-2,6-dioxopiperidin-3-yl)-1h-isoindole-1,3(2h)-dione

N-Methyl-2-phthalimidoglutarimide

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N-METHYL-2-PHTHALIMIDOGLUTARIMIDE

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Synthetic Route

Precursor & DownStream

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.