O-Demethyl Lenvatinib
Modify Date: 2025-08-25 19:27:13
O-Demethyl Lenvatinib structure
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Common Name | O-Demethyl Lenvatinib | ||
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| CAS Number | 417717-04-5 | Molecular Weight | 412.826 | |
| Density | 1.6±0.0 g/cm3 | Boiling Point | 644.1±0.0 °C at 760 mmHg | |
| Molecular Formula | C20H17ClN4O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 343.4±0.0 °C | |
Use of O-Demethyl LenvatinibO-Demethyl Lenvatinib is a metabolite of Lenvatinib (HY-10981). Lenvatinib (E7080) is an oral, multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, shows potent antitumor activities[1][2]. |
| Name | 4-{3-Chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-hydroxy-6-quinolinecarboxamide |
|---|---|
| Synonym | More Synonyms |
| Description | O-Demethyl Lenvatinib is a metabolite of Lenvatinib (HY-10981). Lenvatinib (E7080) is an oral, multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, shows potent antitumor activities[1][2]. |
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| Related Catalog |
| Density | 1.6±0.0 g/cm3 |
|---|---|
| Boiling Point | 644.1±0.0 °C at 760 mmHg |
| Molecular Formula | C20H17ClN4O4 |
| Molecular Weight | 412.826 |
| Flash Point | 343.4±0.0 °C |
| Exact Mass | 412.093842 |
| LogP | 4.23 |
| Vapour Pressure | 0.0±0.0 mmHg at 25°C |
| Index of Refraction | 1.739 |
| Water Solubility | Insuluble (6.2E-5 g/L) (25 ºC) |
| 6-Quinolinecarboxamide, 4-[3-chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-hydroxy- |
| 4-{3-Chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-hydroxy-6-quinolinecarboxamide |
| 4-[3-Chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-hydroxy-6-quinolinecarboxamide |
| Lenvatinib Impurity 4 |