lipiferolide

Modify Date: 2024-01-13 20:29:43

lipiferolide structure	Common Name	lipiferolide
	CAS Number	41059-80-7	Molecular Weight	306.35
	Density	1.2±0.1 g/cm3	Boiling Point	444.8±45.0 °C at 760 mmHg
	Molecular Formula	C₁₇H₂₂O₅	Melting Point	118-119 °C
	MSDS	N/A	Flash Point	196.3±28.8 °C

Use of lipiferolide

Lipiferolide is an antiplasmodial agent (IC50: 1.8 μg/mL) that can be isolated from Liriodendron tulipifera. Lipiferolide also inhibits FPTase, and has antitumor activity[1][2].

Name	8.β.-Acetoxy-parthenolide
Synonym	More Synonyms

Description	Lipiferolide is an antiplasmodial agent (IC50: 1.8 μg/mL) that can be isolated from Liriodendron tulipifera. Lipiferolide also inhibits FPTase, and has antitumor activity[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> Farnesyl Transferase
References	[1]. Graziose R, et al. Antiplasmodial activity of aporphine alkaloids and sesquiterpene lactones from Liriodendron tulipifera L. J Ethnopharmacol. 2011 Jan 7;133(1):26-30. [2]. Moon MK, et al. Farnesyl protein transferase and tumor cell growth inhibitory activities of lipiferolide isolated from Liriodendron tulipifera. Arch Pharm Res. 2007 Mar;30(3):299-302.

Description

Lipiferolide is an antiplasmodial agent (IC50: 1.8 μg/mL) that can be isolated from Liriodendron tulipifera. Lipiferolide also inhibits FPTase, and has antitumor activity[1][2].

Related Catalog

Research Areas >> Infection

Signaling Pathways >> Metabolic Enzyme/Protease >> Farnesyl Transferase

References

[1]. Graziose R, et al. Antiplasmodial activity of aporphine alkaloids and sesquiterpene lactones from Liriodendron tulipifera L. J Ethnopharmacol. 2011 Jan 7;133(1):26-30.

[2]. Moon MK, et al. Farnesyl protein transferase and tumor cell growth inhibitory activities of lipiferolide isolated from Liriodendron tulipifera. Arch Pharm Res. 2007 Mar;30(3):299-302.

Density	1.2±0.1 g/cm3
Boiling Point	444.8±45.0 °C at 760 mmHg
Melting Point	118-119 °C
Molecular Formula	C₁₇H₂₂O₅
Molecular Weight	306.35
Flash Point	196.3±28.8 °C
Exact Mass	306.146729
PSA	65.13000
LogP	2.13
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.531