Methyl 5-(hydroxymethyl)-2-pyridinecarboxylate

Modify Date: 2025-09-21 11:57:38

Methyl 5-(hydroxymethyl)-2-pyridinecarboxylate Structure
Methyl 5-(hydroxymethyl)-2-pyridinecarboxylate structure
Common Name Methyl 5-(hydroxymethyl)-2-pyridinecarboxylate
CAS Number 39977-42-9 Molecular Weight 167.162
Density 1.2±0.1 g/cm3 Boiling Point 335.8±32.0 °C at 760 mmHg
Molecular Formula C8H9NO3 Melting Point N/A
MSDS N/A Flash Point 156.9±25.1 °C

 Names

Name methyl 5-(hydroxymethyl)pyridine-2-carboxylate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 335.8±32.0 °C at 760 mmHg
Molecular Formula C8H9NO3
Molecular Weight 167.162
Flash Point 156.9±25.1 °C
Exact Mass 167.058243
PSA 59.42000
LogP -0.68
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.546

 Synthetic Route

~86%

Methyl 5-(hydroxymethyl)-2-pyridinecarboxylate Structure

Methyl 5-(hydro...

CAS#:39977-42-9

Literature: Chen, Xi-Bo; Hu, Qiu-Peng; Yuan, Qian-Jia; Ding, Wei; Ren, Jiangmeng; Zeng, Bu-Bing Tetrahedron Letters, 2012 , vol. 53, # 29 p. 3798 - 3801

~63%

Methyl 5-(hydroxymethyl)-2-pyridinecarboxylate Structure

Methyl 5-(hydro...

CAS#:39977-42-9

Literature: BRISTOL-MYERS SQUIBB COMPANY; GAVAI, Ashvinikumar V.; ZHAO, Yufen; O'MALLEY, Daniel; QUESNELLE, Claude A.; FINK, Brian E.; NORRIS, Derek J.; HAN, Wen-Ching; DELUCCA, George V. Patent: WO2014/47374 A1, 2014 ; Location in patent: Paragraph 00379 ;

~%

Methyl 5-(hydroxymethyl)-2-pyridinecarboxylate Structure

Methyl 5-(hydro...

CAS#:39977-42-9

Literature: BRISTOL-MYERS SQUIBB COMPANY; GAVAI, Ashvinikumar V.; ZHAO, Yufen; O'MALLEY, Daniel; QUESNELLE, Claude A.; FINK, Brian E.; NORRIS, Derek J.; HAN, Wen-Ching; DELUCCA, George V. Patent: WO2014/47374 A1, 2014 ;

~%

Methyl 5-(hydroxymethyl)-2-pyridinecarboxylate Structure

Methyl 5-(hydro...

CAS#:39977-42-9

Literature: BRISTOL-MYERS SQUIBB COMPANY; GAVAI, Ashvinikumar V.; ZHAO, Yufen; O'MALLEY, Daniel; QUESNELLE, Claude A.; FINK, Brian E.; NORRIS, Derek J.; HAN, Wen-Ching; DELUCCA, George V. Patent: WO2014/47374 A1, 2014 ;

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

2-Pyridinecarboxylic acid, 5-(hydroxymethyl)-, methyl ester
methyl 5-hydroxymethyl-2-pyridinecarboxylate
5-HYDROXYMETHYL-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
Methyl 5-(hydroxymethyl)-2-pyridinecarboxylate
methyl 5-(hydroxymethyl)picolinate
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