Reticuline

Modify Date: 2024-01-06 10:26:13

Reticuline structure	Common Name	Reticuline
	CAS Number	3968-19-2	Molecular Weight	329.390
	Density	1.2±0.1 g/cm3	Boiling Point	504.9±50.0 °C at 760 mmHg
	Molecular Formula	C₁₉H₂₃NO₄	Melting Point	N/A
	MSDS	N/A	Flash Point	259.2±30.1 °C

Use of Reticuline

(R)-Reticuline is an isomer of Reticuline (HY-N1356). Reticuline displays anti-inflammatory and cardiovascular effects through JAK2/STAT3 and NF-κB signaling pathways. Salutaridine is a key intermediate in morphine biosynthesis. Salutaridine can be converted from (R)-Reticuline in the poppy plant. The conversion system relies on membrane-bound cytochrome P-450 enzymes and also requires reducing cofactors NADPH, molecular oxygen, etc[1][2].

Name	(R)-reticuline
Synonym	More Synonyms

Description	(R)-Reticuline is an isomer of Reticuline (HY-N1356). Reticuline displays anti-inflammatory and cardiovascular effects through JAK2/STAT3 and NF-κB signaling pathways. Salutaridine is a key intermediate in morphine biosynthesis. Salutaridine can be converted from (R)-Reticuline in the poppy plant. The conversion system relies on membrane-bound cytochrome P-450 enzymes and also requires reducing cofactors NADPH, molecular oxygen, etc[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Gerardy R, et al. Formation of salutaridine from (R)-reticuline by a membrane-bound cytochrome P-450 enzyme from Papaver somniferum[J]. Phytochemistry, 1992, 32(1): 79-86. [2]. Yang X, et al. Anti-Inflammatory Effects of Boldine and Reticuline Isolated from Litsea cubeba through JAK2/STAT3 and NF-κB Signaling Pathways. Planta Med. 2018 Jan;84(1):20-25.

Description

Related Catalog

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

References

[1]. Gerardy R, et al. Formation of salutaridine from (R)-reticuline by a membrane-bound cytochrome P-450 enzyme from Papaver somniferum[J]. Phytochemistry, 1992, 32(1): 79-86.

[2]. Yang X, et al. Anti-Inflammatory Effects of Boldine and Reticuline Isolated from Litsea cubeba through JAK2/STAT3 and NF-κB Signaling Pathways. Planta Med. 2018 Jan;84(1):20-25.

Density	1.2±0.1 g/cm3
Boiling Point	504.9±50.0 °C at 760 mmHg
Molecular Formula	C₁₉H₂₃NO₄
Molecular Weight	329.390
Flash Point	259.2±30.1 °C
Exact Mass	329.162720
PSA	62.16000
LogP	2.09
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.604

1-(3-Hydroxy-4-methoxybenzyl)-6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-ol

Reticuline

1,2,3,4-Tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methyl-7-isoquinolinol

2-Methyl-7-hydroxy-6-methoxy-1-(3-hydroxy-4-methoxybenzyl)-1,2,3,4-tetrahydroisoquinoline

1-(3-Hydroxy-4-methoxybenzyl)-6-methoxy-2-methyl-1,2,3,4-tetrahydro-7-isoquinolinol

Coclanoline

(R)-Reticuline

(1R)-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol

(±)-Reticuline

7-Isoquinolinol, 1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methyl-

Reticuline

Use of Reticuline

Names

Reticuline Biological Activity

Chemical & Physical Properties

Synonyms