CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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DI2400000
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CHEMICAL NAME :
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Benzo(b)(1,5)naphthyridine, 7-chloro-10-(3-(N-(2-chloroethyl)-N-ethyl)aminopropyl amino)- 2-methoxy-, dihydrochloride
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CAS REGISTRY NUMBER :
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38915-28-5
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LAST UPDATED :
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199410
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DATA ITEMS CITED :
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7
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MOLECULAR FORMULA :
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C20-H24-Cl2-N4-O.2Cl-H
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MOLECULAR WEIGHT :
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480.30
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WISWESSER LINE NOTATION :
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T C666 BN GNJ FO1 IM3N2&2G MG &GH 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD20 - Lethal Dose
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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3737 ug/kg
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TOXIC EFFECTS :
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Tumorigenic - active as anti-cancer agent
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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7 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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4800 ug/kg
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TOXIC EFFECTS :
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Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors
MUTATION DATA
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TYPE OF TEST :
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Mutation in mammalian somatic cells
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TEST SYSTEM :
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Rodent - hamster Ovary
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DOSE/DURATION :
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1 umol/L
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REFERENCE :
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CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 39,4875,1979
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