BILR 355

Modify Date: 2025-08-25 10:13:14

BILR 355 Structure
BILR 355 structure
 Common Name BILR 355
CAS Number 380378-81-4 Molecular Weight 441.48200
Density N/A Boiling Point N/A
Molecular Formula C25H23N5O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BILR 355


BILR 355 is a second-generation nonnucleoside reverse transcriptase inhibitor (NNRTI). BILR 355 is highly specific toward HIV-1 reverse transcriptase (RT). BILR 355 can be used for HIV infections research[1].

 Names

Name 11-ethyl-5-methyl-8-[2-(1-oxidoquinolin-1-ium-4-yl)oxyethyl]dipyrido[2,3-d:2',3'-h][1,4]diazepin-6-one
Synonym More Synonyms

 BILR 355 Biological Activity

Description BILR 355 is a second-generation nonnucleoside reverse transcriptase inhibitor (NNRTI). BILR 355 is highly specific toward HIV-1 reverse transcriptase (RT). BILR 355 can be used for HIV infections research[1].
Related Catalog
References

[1]. Fenglei Huang, et al. Pharmacokinetic and safety evaluation of BILR 355, a second-generation nonnucleoside reverse transcriptase inhibitor, in healthy volunteers. Antimicrob Agents Chemother. 2008 Dec;52(12):4300-7.  

 Chemical & Physical Properties

Molecular Formula C25H23N5O3
Molecular Weight 441.48200
Exact Mass 441.18000
PSA 87.40000
LogP 4.06850

 Synthetic Route

11-ethyl-5-methyl-8-(2-quinolin-4-yloxyethyl)dipyrido[2,3-d:2',3'-h][1,4]diazepin-6-one structure

11-ethyl-5-meth...

CAS#:380378-84-7

~74%

BILR 355 Structure

BILR 355

CAS#:380378-81-4

Literature: Simoneau, Bruno Patent: US2002/28807 A1, 2002 ;
N/A structure

N/A

CAS#:886468-35-5

~85%

BILR 355 Structure

BILR 355

CAS#:380378-81-4

Literature: Busacca, Carl A.; Cerreta, Mike; Dong, Yong; Eriksson, Magnus C.; Farina, Vittorio; Feng, XuWu; Kim, Ji-Young; Lorenz, Jon C.; Sarvestani, Max; Simpson, Robert; Varsolona, Rieh; Vitous, Jana; Campbell, Scot J.; Davis, Mark S.; Jones, Paul-James; Norwood, Daniel; Qiu, Fenghe; Beaulieu, Pierre L.; Duceppe, Jean-Simon; Hache, Bruno; Brong, Jim; Chiu, Fang-Ting; Curtis, Tom; Kelley, Jason; Lo, Young S.; Powner, Tory H. Organic Process Research and Development, 2008 , vol. 12, # 4 p. 603 - 613
2-Hydroxy acid structure

2-Hydroxy acid

CAS#:609-71-2

~%

BILR 355 Structure

BILR 355

CAS#:380378-81-4

Literature: Busacca, Carl A.; Cerreta, Mike; Dong, Yong; Eriksson, Magnus C.; Farina, Vittorio; Feng, XuWu; Kim, Ji-Young; Lorenz, Jon C.; Sarvestani, Max; Simpson, Robert; Varsolona, Rieh; Vitous, Jana; Campbell, Scot J.; Davis, Mark S.; Jones, Paul-James; Norwood, Daniel; Qiu, Fenghe; Beaulieu, Pierre L.; Duceppe, Jean-Simon; Hache, Bruno; Brong, Jim; Chiu, Fang-Ting; Curtis, Tom; Kelley, Jason; Lo, Young S.; Powner, Tory H. Organic Process Research and Development, 2008 , vol. 12, # 4 p. 603 - 613
5-bromo-2-hydroxynicotinic acid structure

5-bromo-2-hydro...

CAS#:104612-36-4

~%

BILR 355 Structure

BILR 355

CAS#:380378-81-4

Literature: Busacca, Carl A.; Cerreta, Mike; Dong, Yong; Eriksson, Magnus C.; Farina, Vittorio; Feng, XuWu; Kim, Ji-Young; Lorenz, Jon C.; Sarvestani, Max; Simpson, Robert; Varsolona, Rieh; Vitous, Jana; Campbell, Scot J.; Davis, Mark S.; Jones, Paul-James; Norwood, Daniel; Qiu, Fenghe; Beaulieu, Pierre L.; Duceppe, Jean-Simon; Hache, Bruno; Brong, Jim; Chiu, Fang-Ting; Curtis, Tom; Kelley, Jason; Lo, Young S.; Powner, Tory H. Organic Process Research and Development, 2008 , vol. 12, # 4 p. 603 - 613
8-bromo-11-ethyl-5H-dipyrido[2,3-d:2',3'-h][1,4]diazepin-6-one structure

8-bromo-11-ethy...

CAS#:134698-42-3

~%

BILR 355 Structure

BILR 355

CAS#:380378-81-4

Literature: Busacca, Carl A.; Cerreta, Mike; Dong, Yong; Eriksson, Magnus C.; Farina, Vittorio; Feng, XuWu; Kim, Ji-Young; Lorenz, Jon C.; Sarvestani, Max; Simpson, Robert; Varsolona, Rieh; Vitous, Jana; Campbell, Scot J.; Davis, Mark S.; Jones, Paul-James; Norwood, Daniel; Qiu, Fenghe; Beaulieu, Pierre L.; Duceppe, Jean-Simon; Hache, Bruno; Brong, Jim; Chiu, Fang-Ting; Curtis, Tom; Kelley, Jason; Lo, Young S.; Powner, Tory H. Organic Process Research and Development, 2008 , vol. 12, # 4 p. 603 - 613
5-bromo-2-chloropyridine-3-carbonyl chloride structure

5-bromo-2-chlor...

CAS#:78686-86-9

~%

BILR 355 Structure

BILR 355

CAS#:380378-81-4

Literature: Busacca, Carl A.; Cerreta, Mike; Dong, Yong; Eriksson, Magnus C.; Farina, Vittorio; Feng, XuWu; Kim, Ji-Young; Lorenz, Jon C.; Sarvestani, Max; Simpson, Robert; Varsolona, Rieh; Vitous, Jana; Campbell, Scot J.; Davis, Mark S.; Jones, Paul-James; Norwood, Daniel; Qiu, Fenghe; Beaulieu, Pierre L.; Duceppe, Jean-Simon; Hache, Bruno; Brong, Jim; Chiu, Fang-Ting; Curtis, Tom; Kelley, Jason; Lo, Young S.; Powner, Tory H. Organic Process Research and Development, 2008 , vol. 12, # 4 p. 603 - 613
6H-Dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one,8-bromo-11-ethyl-5,11-dihydro-5-methyl- structure

6H-Dipyrido[3,2...

CAS#:162109-00-4

~%

BILR 355 Structure

BILR 355

CAS#:380378-81-4

Literature: Busacca, Carl A.; Cerreta, Mike; Dong, Yong; Eriksson, Magnus C.; Farina, Vittorio; Feng, XuWu; Kim, Ji-Young; Lorenz, Jon C.; Sarvestani, Max; Simpson, Robert; Varsolona, Rieh; Vitous, Jana; Campbell, Scot J.; Davis, Mark S.; Jones, Paul-James; Norwood, Daniel; Qiu, Fenghe; Beaulieu, Pierre L.; Duceppe, Jean-Simon; Hache, Bruno; Brong, Jim; Chiu, Fang-Ting; Curtis, Tom; Kelley, Jason; Lo, Young S.; Powner, Tory H. Organic Process Research and Development, 2008 , vol. 12, # 4 p. 603 - 613
isopropyl 2-cyano-2-(11-ethyl-5-methyl-6-oxo-6,11-dihydro-5H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-8-yl)acetate structure

isopropyl 2-cya...

CAS#:639469-44-6

~%

BILR 355 Structure

BILR 355

CAS#:380378-81-4

Literature: Busacca, Carl A.; Cerreta, Mike; Dong, Yong; Eriksson, Magnus C.; Farina, Vittorio; Feng, XuWu; Kim, Ji-Young; Lorenz, Jon C.; Sarvestani, Max; Simpson, Robert; Varsolona, Rieh; Vitous, Jana; Campbell, Scot J.; Davis, Mark S.; Jones, Paul-James; Norwood, Daniel; Qiu, Fenghe; Beaulieu, Pierre L.; Duceppe, Jean-Simon; Hache, Bruno; Brong, Jim; Chiu, Fang-Ting; Curtis, Tom; Kelley, Jason; Lo, Young S.; Powner, Tory H. Organic Process Research and Development, 2008 , vol. 12, # 4 p. 603 - 613
4-quinolone structure

4-quinolone

CAS#:611-36-9

~%

BILR 355 Structure

BILR 355

CAS#:380378-81-4

Literature: Busacca, Carl A.; Cerreta, Mike; Dong, Yong; Eriksson, Magnus C.; Farina, Vittorio; Feng, XuWu; Kim, Ji-Young; Lorenz, Jon C.; Sarvestani, Max; Simpson, Robert; Varsolona, Rieh; Vitous, Jana; Campbell, Scot J.; Davis, Mark S.; Jones, Paul-James; Norwood, Daniel; Qiu, Fenghe; Beaulieu, Pierre L.; Duceppe, Jean-Simon; Hache, Bruno; Brong, Jim; Chiu, Fang-Ting; Curtis, Tom; Kelley, Jason; Lo, Young S.; Powner, Tory H. Organic Process Research and Development, 2008 , vol. 12, # 4 p. 603 - 613

 Synonyms

5-ethyl-10-methyl-2-[2-(1-oxyquinolin-4-yloxy)ethyl]-5,10-dihydro-4,5,6,10-tetraazadibenzo[a,d]cyclohepten-11-one
BILR 355 BS
6H-Dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one,11-ethyl-5,11-dihydro-5-methyl-8-[2-[(1-oxido-4-quinolinyl)oxy]ethyl]
DIP007
6H-Dipyrido[2,3-e:3',2'-b][1,4]diazepin-6-one,11-ethyl-5,11-dihydro-5-methyl-8-[2-[(1-oxido-4-quinolinyl)oxy]ethyl]
5,11-dihydro-11-ethyl-5-methyl-8-{2-{(1-oxido-4-quinolinyl)oxy}ethyl}-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one HCl
5,11-dihydro-11-ethyl-5-methyl-8-{2-{(4-quinolinyl)oxy}ethyl}-6H-dipyrido[3,2-b:2',3'-e]10 [1,4]diazepin-6-one HCl
5,11-dihydro-11-ethyl-5-methyl-8-{2-{(1-oxido-4-quinolinyl)oxy}ethyl}-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here
Related Compounds: More...
1-prop-2-ynyl-6-(3-pyridyl)imidazo[1,2-b]pyrazole
2098055-01-5
2-[6-(3-pyridyl)imidazo[1,2-b]pyrazol-1-yl]acetonitrile
2098030-38-5
2-[6-(3-pyridyl)imidazo[1,2-b]pyrazol-1-yl]ethanol
2098091-83-7
1-(2-chloroethyl)-6-(3-pyridyl)imidazo[1,2-b]pyrazole
2098030-44-3
2-[6-(3-pyridyl)imidazo[1,2-b]pyrazol-1-yl]ethanamine
2097950-38-2
6-(4-pyridyl)-5H-imidazo[1,2-b]pyrazole
2097968-99-3
1-methyl-6-(4-pyridyl)imidazo[1,2-b]pyrazole
2097950-45-1
1-ethyl-6-(4-pyridyl)imidazo[1,2-b]pyrazole
2098055-18-4
1-isopropyl-6-(4-pyridyl)imidazo[1,2-b]pyrazole
2097950-49-5
1-prop-2-ynyl-6-(4-pyridyl)imidazo[1,2-b]pyrazole
2098091-88-2
Chemsrc provides BILR 355(CAS#:380378-81-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of BILR 355 are included as well.>> amp version: BILR 355

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved