Phenothiazine, 10-(3-(beta-morpholinoethylamino)propyl)-2-trifluoromethyl-, dihydrochloride

Modify Date: 2024-01-08 18:31:29

Phenothiazine, 10-(3-(beta-morpholinoethylamino)propyl)-2-trifluoromethyl-, dihydrochloride structure	Common Name	Phenothiazine, 10-(3-(beta-morpholinoethylamino)propyl)-2-trifluoromethyl-, dihydrochloride
	CAS Number	3772-70-1	Molecular Weight	473.98200
	Density	1.247g/cm3	Boiling Point	547.9ºC at 760 mmHg
	Molecular Formula	C₂₂H₂₇ClF₃N₃OS	Melting Point	N/A
	MSDS	N/A	Flash Point	285.1ºC

Name	Phenothiazine, 10-(3-(β-morpholinoethylamino)propyl)-2-trifluoromethyl-, dihydrochloride

Density	1.247g/cm3
Boiling Point	547.9ºC at 760 mmHg
Molecular Formula	C₂₂H₂₇ClF₃N₃OS
Molecular Weight	473.98200
Flash Point	285.1ºC
Exact Mass	473.15200
PSA	53.04000
LogP	5.81580
Index of Refraction	1.565

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SP3325000

CHEMICAL NAME :: Phenothiazine, 10-(3-(beta-morpholinoethylamino)propyl)-2-trifluorom ethyl-, dihydrochloride

CAS REGISTRY NUMBER :: 3772-70-1

LAST UPDATED :: 199712

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C22-H26-F3-N3-O-S.2Cl-H

MOLECULAR WEIGHT :: 510.49

WISWESSER LINE NOTATION :: T C666 BN ISJ EXFFF B3N2&- AT6N DOTJ &GH 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 616 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - chromodacryorrhea Sense Organs and Special Senses (Eye) - ptosis Behavioral - rigidity (including catalepsy)

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 136,476,1962

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - chromodacryorrhea Sense Organs and Special Senses (Eye) - ptosis Behavioral - rigidity (including catalepsy)

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 136,476,1962

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 45 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 136,476,1962

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