4-Methoxy-7H-pyrimido[4,5-b][1,4]thiazin-6-amine

Modify Date: 2023-02-06 14:28:33

4-Methoxy-7H-pyrimido[4,5-b][1,4]thiazin-6-amine Structure
4-Methoxy-7H-pyrimido[4,5-b][1,4]thiazin-6-amine structure
Common Name 4-Methoxy-7H-pyrimido[4,5-b][1,4]thiazin-6-amine
CAS Number 37497-00-0 Molecular Weight 196.23000
Density 1.64g/cm3 Boiling Point 456.8ºC at 760 mmHg
Molecular Formula C7H8N4OS Melting Point N/A
MSDS N/A Flash Point 230.1ºC

 Names

Name 4-Methoxy-7H-pyrimido[4,5-b][1,4]thiazin-6-amine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.64g/cm3
Boiling Point 456.8ºC at 760 mmHg
Molecular Formula C7H8N4OS
Molecular Weight 196.23000
Flash Point 230.1ºC
Exact Mass 196.04200
PSA 98.69000
LogP 0.71550
Index of Refraction 1.774
InChIKey BSYNHAHDUKAHAL-UHFFFAOYSA-N
SMILES COc1ncnc2c1N=C(N)CS2

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UW7864000
CHEMICAL NAME :
7H-Pyrimido(4,5-b)(1,4)thiazine, 6-amino-4-methoxy-
CAS REGISTRY NUMBER :
37497-00-0
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C7-H8-N4-O-S
MOLECULAR WEIGHT :
196.25
WISWESSER LINE NOTATION :
T66 BN DN GN JS IHJ EO1 HZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Tumorigenic - active as anti-cancer agent Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other oxidoreductases
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 11,1205,1977

 Safety Information

HS Code 2934999090

 Synthetic Route

~%

4-Methoxy-7H-pyrimido[4,5-b][1,4]thiazin-6-amine Structure

4-Methoxy-7H-py...

CAS#:37497-00-0

Literature: Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 8, p. 859 - 863 Khimiya Geterotsiklicheskikh Soedinenii, , vol. 8, # 7 p. 944 - 948

 Precursor & DownStream

Precursor  2

DownStream  0

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

4-Methoxy-7H-pyrimido(4,5-b)(1,4)thiazin-6-amine
Thomizin-Base
4-Methoxy-6-aminopyrimido<4,5-b>-1,4-thiazin
4-Methoxy-6-aminopyrimido<4,5-b>(1,4)thiazine
7H-Pyrimido(4,5-b)(1,4)thiazine,6-amino-4-methoxy
6-Amino-4-methoxy-7H-pyrimido(4,5-b)(1,4)thiazine
4-methoxy-7H-pyrimido[4,5-b][1,4]thiazin-6-ylamine
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