Bucladesine

Modify Date: 2024-01-03 16:33:55

Bucladesine structure	Common Name	Bucladesine
	CAS Number	362-74-3	Molecular Weight	469.386
	Density	1.7±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₁₈H₂₄N₅O₈P	Melting Point	203 - 205 °C
	MSDS	N/A	Flash Point	N/A

Use of Bucladesine

Bucladesine is a cyclic nucleotide derivative which mimics the action of endogenous cAMP and is capable of permeating the cell membrane. It has vasodilator properties and is used as a cardiac stimulant. Bucladesine is a phosphodiesterase inhibitor. Bucladesine is a cell permeable cAMP analog. The compound is used in a wide variety of research applications because it mimics cAMP and can induce normal physiological responses when added to cells in experimental conditions. cAMP is only able to elicit minimal responses in these situations. The neurite outgrowth instigated by bucladesine in cell cultures has been shown to be enhanced by nardosinone.

Name	Bucladesine
Synonym	More Synonyms

Density	1.7±0.1 g/cm3
Melting Point	203 - 205 °C
Molecular Formula	C₁₈H₂₄N₅O₈P
Molecular Weight	469.386
Exact Mass	469.136261
PSA	173.80000
LogP	1.76300
Index of Refraction	1.717

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ES5055000

CHEMICAL NAME :: Butyramide, N-(9-beta-D-ribofuranosyl-9H-furin-6-yl)-, cyclic 3',5'-(hydrogen phosphate) 2'- butyrate

CAS REGISTRY NUMBER :: 362-74-3

LAST UPDATED :: 199612

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C18-H24-N5-O8-P

MOLECULAR WEIGHT :: 469.44

WISWESSER LINE NOTATION :: T56 BO FOPOTJ DOV3 GQ GO C- DT56 BN DN FN HNJ IMV3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Rodent - mouse Cells - not otherwise specified

DOSE/DURATION :: 50 umol/L

REFERENCE :: JIDEAE Journal of Investigative Dermatology. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1938- Volume(issue)/page/year: 66,313,1976

dibutyryl cAMP

Bt2 cyclic AMP

(4aR,6R,7R,7aR)-6-[6-(butanoylamino)-9H-purin-9-yl]-2-hydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-yl butanoate

3',5'-Cyclic AMP dibutyrate

n-6,o-2'-dibutyryl adenosine cyclic 3':5'-monophosphate

Cyclic AMP dibutyrate

N-(9-b-D-Ribofuranosyl-9H-purin-6-yl)butyramide Cyclic 3',5'-(Hydrogen Phosphate) 2'-Butyrate

N6,2'-O-Dibutyryl cAMP

N6,2'-O-Dibutyryladenosine 3',5'-Cyclic Monophosphate

Butanoic acid, (4aR,6R,7R,7aR)-tetrahydro-2-hydroxy-2-oxido-6-[6-[(1-oxobutyl)amino]-9H-purin-9-yl]-4H-furo[3,2-d]-1,3,2-dioxaphosphorin-7-yl ester

N6,2'-O-dibutyryl-cAMP

Bucladesine

(4aR,6R,7R,7aR)-6-[6-(Butyrylamino)-9H-purin-9-yl]-2-hydroxy-2-oxidotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-yl butyrate

Dibutyryl cyclic 3',5'-AMP

dibutyryl cyclic AMP

CalciuM Dibutyacyladenosine

N,O-dibutyryl cyclic AMP

N-(9-beta-D-Ribofuranosyl-9H-furin-6-yl)-butyramidecyclic3',5'-(hydrogenphosphate)2'-butyrate

N-(1-Oxobutyl)adenosine Cyclic 3',5'-(Hydrogen Phosphate) 2'-Butanoate

Dibutyryl-cAMP

Dibutyryl 3',5'-Cyclic AMP

DC Chemicals Limited
China
Product Name: Bucladesine
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Bucladesine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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