Bumadizone

Modify Date: 2024-01-04 17:09:54

Bumadizone Structure
Bumadizone structure
 Common Name Bumadizone
CAS Number 3583-64-0 Molecular Weight 326.39000
Density 1.227g/cm3 Boiling Point 487.4ºC at 760mmHg
Molecular Formula C19H22N2O3 Melting Point N/A
MSDS N/A Flash Point 248.6ºC

 Use of Bumadizone


Bumadizone is a non-steroidal anti-inflammatory drug (NSAID) and can relieve pain[1].

 Names

Name bumadizone
Synonym More Synonyms

 Bumadizone Biological Activity

Description Bumadizone is a non-steroidal anti-inflammatory drug (NSAID) and can relieve pain[1].
Related Catalog
In Vitro Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used in the chronic inflammatoryconditions.
References

[1]. Samia A Nour, et al. Bumadizone calcium dihydrate microspheres compressed tablets for colon targeting: formulation, optimization and in vivo evaluation in rabbits. Drug Deliv. 2015 May;22(3):286-97.

 Chemical & Physical Properties

Density 1.227g/cm3
Boiling Point 487.4ºC at 760mmHg
Molecular Formula C19H22N2O3
Molecular Weight 326.39000
Flash Point 248.6ºC
Exact Mass 326.16300
PSA 69.64000
LogP 4.01070
Index of Refraction 1.628

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OO0623000
CHEMICAL NAME :
Malonic acid, butyl-, mono(1,2-diphenylhydrazide)
CAS REGISTRY NUMBER :
3583-64-0
LAST UPDATED :
199712
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C19-H22-N2-O3
MOLECULAR WEIGHT :
326.43

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1350 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 67,337,1971
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
270 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 67,337,1971

 Safety Information

HS Code 2928000090

 Precursor & DownStream

Precursor  1

DownStream  0

 Customs

HS Code 2928000090
Summary 2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

 Synonyms

Butyramide,N-sec-butyl
(+-)-Buttersaeure-sec-butylamid
2-[(1,2-Diphenylhydrazino)carbonyl]hexanoic acid
Butanamide,N-(1-methylpropyl)
N-(2-Carboxy-hexanoyl)-hydrazobenzol
N-s-Butyl-butyramide
N-sec-butyl-butyramide
N-(2-carboxycaproyl)hydrazobenzene
N-(2-BUTYL)BUTANAMIDE
Bumadizon (14C)
Butylmalonsaeure-N,N'-diphenylmonohydrazid
(+-)-Butylmalonsaeure-mono-<N.N'-diphenyl-hydrazid>
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Related Compounds: More...
bumadizone calcium
34461-73-9
bumadizone calcium hemihydrate
69365-73-7
Chemsrc provides Bumadizone(CAS#:3583-64-0) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Bumadizone are included as well.>> amp version: Bumadizone

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