Chlorin e6 trimethyl ester

Modify Date: 2024-01-09 11:39:14

Chlorin e6 trimethyl ester Structure
Chlorin e6 trimethyl ester structure
Common Name Chlorin e6 trimethyl ester
CAS Number 35038-32-5 Molecular Weight 638.75300
Density 1.25g/cm3 Boiling Point 704.8ºC at 760 mmHg
Molecular Formula C37H42N4O6 Melting Point N/A
MSDS N/A Flash Point 189.4ºC

 Use of Chlorin e6 trimethyl ester


Chlorin e6 trimethyl ester, a methyl pheophorbide-a derivative, and is a photosensitizer that can be used in photodynamic therapy (PDT)[1][2].

 Names

Name methyl (2S-trans)-13-ethyl-2,3-dihydro-18-(methoxycarbonyl)-20-(2-methoxy-2-oxoethyl)-3,7,12,17-tetramethyl-8-vinyl-21H,23H-porphine-2-propionate

 Chlorin e6 trimethyl ester Biological Activity

Description Chlorin e6 trimethyl ester, a methyl pheophorbide-a derivative, and is a photosensitizer that can be used in photodynamic therapy (PDT)[1][2].
Related Catalog
In Vivo Chlorin e6 trimethyl ester (5 mg/kg; i.p.) has no tumorcidal activity in mice[1].
References

[1]. Pandey RK, et, al. Chlorin and porphyrin derivatives as potential photosensitizers in photodynamic therapy. Photochemistry and Photobiology. 1991. 53(1):65-72.

[2]. Bauer D, et, al. Functionalization of chlorin e6 trimethylester towards potential amphiphilic photosensitizers for photodynamic therapy. Journal of Porphyrins and Phthalocyanines. 2019. 23(3): 243-250.

 Chemical & Physical Properties

Density 1.25g/cm3
Boiling Point 704.8ºC at 760 mmHg
Molecular Formula C37H42N4O6
Molecular Weight 638.75300
Flash Point 189.4ºC
Exact Mass 638.31000
PSA 131.44000
LogP 5.19190
Index of Refraction 1.618