5-Methylurapidil
5-Methylurapidil structure
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Common Name | 5-Methylurapidil | ||
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| CAS Number | 34661-85-3 | Molecular Weight | 437.96300 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H32ClN5O3 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of 5-Methylurapidil5-Methylurapidil isα1A‐adrenoceptor antagonist. 5-Methylurapidil can be used for the research of cardiovascular diseases such as hypertension and heart failure[1]. |
| Name | 6-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylamino]-1,3,5-trimethylpyrimidine-2,4-dione,hydrochloride |
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| Synonym | More Synonyms |
| Description | 5-Methylurapidil isα1A‐adrenoceptor antagonist. 5-Methylurapidil can be used for the research of cardiovascular diseases such as hypertension and heart failure[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C21H32ClN5O3 |
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| Molecular Weight | 437.96300 |
| Exact Mass | 437.21900 |
| PSA | 71.74000 |
| LogP | 1.90310 |
| InChIKey | HIHZDNKKIUQQSC-UHFFFAOYSA-N |
| SMILES | COc1ccccc1N1CCN(CCCNc2c(C)c(=O)n(C)c(=O)n2C)CC1 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
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Cell membrane chromatography competitive binding analysis for characterization of α1A adrenoreceptor binding interactions.
Anal. Bioanal. Chem 400(10) , 3625-33, (2011) A new high α(1A) adrenoreceptor (α(1A)AR) expression cell membrane chromatography (CMC) method was developed for characterization of α(1A)AR binding interactions. HEK293 α(1A) cell line, which express... |
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Influence of high dietary sodium intake on the functional subtypes of alpha-adrenoceptors in the renal cortical vasculature of Wistar-Kyoto rats.
Auton. Autacoid Pharmacol. 29(1-2) , 25-31, (2009) 1 Increased renal vascular resistance is one renal functional abnormality that contributes to hypertension, and alpha(1)-adrenoceptors play a pivotal role in modulating this renal vascular resistance.... |
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Alpha-1A adrenergic receptor activation increases inhibitory tone in CA1 hippocampus.
Epilepsy Res. 84(2-3) , 97-109, (2009) The endogenous catecholamine norepinephrine (NE) exhibits anti-epileptic properties, however it is not well understood which adrenergic receptor (AR) mediates this effect. The aim of this study was to... |
| 5-Methyl-6[[3-[4-(2-methoxyphenyl)-1-piperazinyl]propyl]amino]-1,3-dimethyluracil |