4-Hydroxyacetophenone oxime

Modify Date: 2025-08-25 13:14:50

4-Hydroxyacetophenone oxime Structure
4-Hydroxyacetophenone oxime structure
Common Name 4-Hydroxyacetophenone oxime
CAS Number 34523-34-7 Molecular Weight 151.16300
Density 1.246g/cm3 Boiling Point 294.8ºC at 760mmHg
Molecular Formula C8H9NO2 Melting Point 143 °C
MSDS N/A Flash Point 132.1ºC

 Use of 4-Hydroxyacetophenone oxime


4-Hydroxyacetophenone oxime is an impurity of Acetaminophen (Paracetamol). Acetaminophen is a potent cyclooxygenase-2 (COX-2) and hepatic N-acetyltransferase 2 (NAT2) inhibitor, and used antipyretic and analgesic drug[1][2].

 Names

Name 4-[1-(hydroxyamino)ethylidene]cyclohexa-2,5-dien-1-one
Synonym More Synonyms

 4-Hydroxyacetophenone oxime Biological Activity

Description 4-Hydroxyacetophenone oxime is an impurity of Acetaminophen (Paracetamol). Acetaminophen is a potent cyclooxygenase-2 (COX-2) and hepatic N-acetyltransferase 2 (NAT2) inhibitor, and used antipyretic and analgesic drug[1][2].
Related Catalog
References

[1]. Hinz, B, et al. Acetaminophen (paracetamol) is a selective cyclooxygenase-2 inhibitor in man. FASEB J, 2008. 22(2): p. 383-90.

[2]. Rothen JP, et al. Acetaminophen is an inhibitor of hepatic N-acetyltransferase 2 in vitro and in vivo. Pharmacogenetics. 1998 Dec;8(6):553-9.

 Chemical & Physical Properties

Density 1.246g/cm3
Boiling Point 294.8ºC at 760mmHg
Melting Point 143 °C
Molecular Formula C8H9NO2
Molecular Weight 151.16300
Flash Point 132.1ºC
Exact Mass 151.06300
PSA 52.82000
LogP 1.59040
Index of Refraction 1.591

 Safety Information

Hazard Codes Xn
HS Code 2928000090

 Synthetic Route

~98%

4-Hydroxyacetophenone oxime Structure

4-Hydroxyacetop...

CAS#:34523-34-7

Literature: Baleizao, Carlos; Corma, Avelino; Garcia, Hermenegildo; Leyva, Antonio Journal of Organic Chemistry, 2004 , vol. 69, # 2 p. 439 - 446 Title/Abstract Full Text View citing articles Show Details Corma, Avelino; Garcia, Hermenegildo; Leyva, Antonio Tetrahedron, 2005 , vol. 61, # 41 p. 9848 - 9854

~%

4-Hydroxyacetophenone oxime Structure

4-Hydroxyacetop...

CAS#:34523-34-7

Literature: US6228350 B1, ;

~77%

4-Hydroxyacetophenone oxime Structure

4-Hydroxyacetop...

CAS#:34523-34-7

Literature: Tokmadzhyan Russian Journal of Organic Chemistry, 2011 , vol. 47, # 11 p. 1746 - 1749

~0%

4-Hydroxyacetophenone oxime Structure

4-Hydroxyacetop...

CAS#:34523-34-7

Literature: Journal of Organic Chemistry, , vol. 59, # 19 p. 5814 - 5817

 Customs

HS Code 2928000090
Summary 2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

 Synonyms

p-hydroxyacetophenone oxime
4-hydroxyphenyl methyl ketone oxime
methyl p-hydroxyphenyl ketone oxime
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here




Get all suppliers and price by the below link:

4-Hydroxyacetophenone oxime suppliers

4-Hydroxyacetophenone oxime price