BAD (103-127) (human)

Modify Date: 2025-08-25 11:33:11

BAD (103-127) (human) Structure
BAD (103-127) (human) structure
Common Name BAD (103-127) (human)
CAS Number 331762-68-6 Molecular Weight 3103.47
Density N/A Boiling Point N/A
Molecular Formula C137H212N42O39S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BAD (103-127) (human)


BAD (103-127) (human), the 25-mer Bad peptide, is derived from the BH3 domain of BAD, can antagonize the function of Bcl-xL. BAD (103-127) (human), the 25-mer Bad peptide, is reported to have almost 800-fold higher affinity for Bcl-XL than the 16-mer peptide[1].

 Names

Name BAD (103-127) (human)

 BAD (103-127) (human) Biological Activity

Description BAD (103-127) (human), the 25-mer Bad peptide, is derived from the BH3 domain of BAD, can antagonize the function of Bcl-xL. BAD (103-127) (human), the 25-mer Bad peptide, is reported to have almost 800-fold higher affinity for Bcl-XL than the 16-mer peptide[1].
Related Catalog
References

[1]. Dilraj Lama, et al. Molecular dynamics simulations of pro-apoptotic BH3 peptide helices in aqueous medium: relationship between helix stability and their binding affinities to the anti-apoptotic protein Bcl-X(L). J Comput Aided Mol Des. 2011 May;25(5):413-26.

 Chemical & Physical Properties

Molecular Formula C137H212N42O39S
Molecular Weight 3103.47
InChIKey NLSLFOGIVJOKDC-ZOKDAYPZSA-N
SMILES CSCCC(NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)CNC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(N)=O)NC(=O)C(C)NC(=O)C(C)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(CC(C)C)NC(=O)C(N)CC(N)=O)C(=O)NC(CO)C(=O)NC(CC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(Cc1ccccc1)C(=O)NC(C(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)NC(Cc1ccccc1)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)O)C(C)C
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