HAP-1

Modify Date: 2024-04-07 13:42:33

HAP-1 Structure
HAP-1 structure
Common Name HAP-1
CAS Number 329004-38-8 Molecular Weight 1335.47
Density N/A Boiling Point N/A
Molecular Formula C60H90N18O17 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HAP-1


HAP-1 is a synovial-targeted transduction peptide. HAP-1 facilitates specific internalization of protein complexes into human and rabbit synovial cells. HAP-1 fused to an antimicrobial peptide, (KLAK)2, to generate a proapoptotic peptide DP2[1].

 Names

Name HAP-1

 HAP-1 Biological Activity

Description HAP-1 is a synovial-targeted transduction peptide. HAP-1 facilitates specific internalization of protein complexes into human and rabbit synovial cells. HAP-1 fused to an antimicrobial peptide, (KLAK)2, to generate a proapoptotic peptide DP2[1].
Related Catalog
References

[1]. Mi Z, et al. Identification of a synovial fibroblast-specific protein transduction domain for delivery of apoptotic agents to hyperplastic synovium. Mol Ther. 2003 Aug;8(2):295-305.  

 Chemical & Physical Properties

Molecular Formula C60H90N18O17
Molecular Weight 1335.47
InChIKey OESNJIQESULMGZ-FAHRUCGCSA-N
SMILES CC(C)CC(NC(=O)C(NC(=O)C(C)NC(=O)C(CCCN=C(N)N)NC(=O)C(C)NC(=O)C(Cc1ccccc1)NC(=O)C(CCC(N)=O)NC(=O)C(Cc1cnc[nH]1)NC(=O)C(Cc1ccccc1)NC(=O)C(N)CO)C(C)O)C(=O)NC(C)C(=O)NC(CO)C(=O)O
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