[D-Trp8]-γ-MSH structure
|
Common Name | [D-Trp8]-γ-MSH | ||
|---|---|---|---|---|
| CAS Number | 321351-81-9 | Molecular Weight | 1570.774 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C74H99N21O16S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of [D-Trp8]-γ-MSH[D-Trp8]-γ-MSH is a potent and selective agonist of melanocortin 3 (MC3) receptor, with IC50s of 6.7 nM, 600 nM and 340 nM for hMC3, hMC4 and hMC5, respectively in CHO cells. [D-Trp8]-γ-MSH could provide protection against multiple inflammatory disorders such as rheumatoid arthritis and colitis[1][2]. |
| Name | (D-Trp8)-γ2-MSH trifluoroacetate salt |
|---|---|
| Synonym | More Synonyms |
| Description | [D-Trp8]-γ-MSH is a potent and selective agonist of melanocortin 3 (MC3) receptor, with IC50s of 6.7 nM, 600 nM and 340 nM for hMC3, hMC4 and hMC5, respectively in CHO cells. [D-Trp8]-γ-MSH could provide protection against multiple inflammatory disorders such as rheumatoid arthritis and colitis[1][2]. |
|---|---|
| Related Catalog | |
| Target |
melanocortin 3 (MC3) receptor[1] |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Molecular Formula | C74H99N21O16S |
| Molecular Weight | 1570.774 |
| Exact Mass | 1569.729980 |
| LogP | 1.27 |
| Index of Refraction | 1.685 |
| L-Tyrosyl-L-valyl-L-methionylglycyl-L-histidyl-L-phenylalanyl-L-arginyl-D-tryptophyl-L-α-aspartyl-L-arginyl-L-phenylalanylglycine |
| L-tyrosyl-L-valyl-L-methionylglycyl-L-histidyl-L-phenylalanyl-N5-(diaminomethylidene)-L-ornithyl-D-tryptophyl-L-α-aspartyl-N5-(diaminomethylidene)-L-ornithyl-L-phenylalanylglycine |
| Glycine, L-tyrosyl-L-valyl-L-methionylglycyl-L-histidyl-L-phenylalanyl-L-arginyl-D-tryptophyl-L-α-aspartyl-L-arginyl-L-phenylalanyl- |