(Des-Asp187)-Melanocyte Protein PMEL 17 (185-193) (human, bovine, mouse)

Modify Date: 2025-09-13 09:49:07

(Des-Asp187)-Melanocyte Protein PMEL 17 (185-193) (human, bovine, mouse) Structure
(Des-Asp187)-Melanocyte Protein PMEL 17 (185-193) (human, bovine, mouse) structure
Common Name (Des-Asp187)-Melanocyte Protein PMEL 17 (185-193) (human, bovine, mouse)
CAS Number 319927-23-6 Molecular Weight 890.03400
Density 1.4±0.1 g/cm3 Boiling Point 1071.5±75.0 °C at 760 mmHg
Molecular Formula C42H67N9O12 Melting Point N/A
MSDS N/A Flash Point 601.8±37.1 °C

 Use of (Des-Asp187)-Melanocyte Protein PMEL 17 (185-193) (human, bovine, mouse)


Gp100:209-217 is a gp 100-derived human CTL epitope presented by HLA-A2. Gp100:209-217 is a polypeptide containing eight amino acids. Gp100:209-217 is a potent TGF-β inhibitor and blocks TGF-β signaling pathway[1].

 Names

Name N-[(2S)-2-{[(2S)-2-({[(2S)-1-{N-[(2S)-2-{[(2S,3R)-2-{[(2S,3S)-2-Amino-1-hydroxy-3-methylpentylidene]amino}-1,3-dihydroxybutylidene]amino}-1,5-dihydroxy-5-iminopentylidene]-L-valyl}-2-pyrrolidinyl](hydroxy)methylene}amino)-1-hydroxy-3-phenylpropylidene]amino}-1,3-dihydroxypropylidene]-L-valine
Synonym More Synonyms

  Biological Activity

Description Gp100:209-217 is a gp 100-derived human CTL epitope presented by HLA-A2. Gp100:209-217 is a polypeptide containing eight amino acids. Gp100:209-217 is a potent TGF-β inhibitor and blocks TGF-β signaling pathway[1].
Related Catalog
References

[1]. Terabe M, et, al. Synergistic effect of TGF-β blockade and immunogenic agents on tumors. WO2006089251.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 1071.5±75.0 °C at 760 mmHg
Molecular Formula C42H67N9O12
Molecular Weight 890.03400
Flash Point 601.8±37.1 °C
Exact Mass 889.49100
PSA 341.78000
LogP 5.99
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.621

 Synonyms

N-[(2S)-2-{[(2S)-2-({[(2S)-1-{N-[(2S)-2-{[(2S,3R)-2-{[(2S,3S)-2-Amino-1-hydroxy-3-methylpentylidene]amino}-1,3-dihydroxybutylidene]amino}-1,5-dihydroxy-5-iminopentylidene]-L-valyl}-2-pyrrolidinyl](hydroxy)methylene}amino)-1-hydroxy-3-phenylpropylidene]amino}-1,3-dihydroxypropylidene]-L-valine
L-Valine, N-[(2S)-2-[[(2S)-2-[[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S,3S)-2-amino-1-hydroxy-3-methylpentylidene]amino]-1,3-dihydroxybutylidene]amino]-1,5-dihydroxy-5-iminopentylidene]amino]-3-methyl-1-oxobutyl]-2-pyrrolidinyl]hydroxymethylene]amino]-1-hydroxy-3-phenylpropylidene]amino]-1,3-dihydroxypropylidene]-
(Des-Asp187)-Melanocyte Protein PMEL 17 (185-193) (human, bovine, mouse)
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