HLI-98C

Modify Date: 2025-08-22 19:03:08

HLI-98C Structure
HLI-98C structure
 Common Name HLI-98C
CAS Number 317326-90-2 Molecular Weight 368.73100
Density N/A Boiling Point N/A
Molecular Formula C17H9ClN4O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HLI-98C


HLI98C is a ubiquitin ligase inhibitor. HLI98C inhibits p53 ubiquitylation. HLI98C inhibits HDM2 auto-ubiquitylation[1].

 Names

Name 10-(3-chlorophenyl)-7-nitropyrimido[4,5-b]quinoline-2,4-dione
Synonym More Synonyms

 HLI-98C Biological Activity

Description HLI98C is a ubiquitin ligase inhibitor. HLI98C inhibits p53 ubiquitylation. HLI98C inhibits HDM2 auto-ubiquitylation[1].
Related Catalog
Target

ubiquitin ligase[1]

References

[1]. Yang Y, et al. Small molecule inhibitors of HDM2 ubiquitin ligase activity stabilize and activate p53 in cells. Cancer Cell. 2005 Jun;7(6):547-59.  

 Chemical & Physical Properties

Molecular Formula C17H9ClN4O4
Molecular Weight 368.73100
Exact Mass 368.03100
PSA 113.57000
LogP 3.31200
InChIKey BRCGPVHRBGGGPW-UHFFFAOYSA-N
SMILES O=c1nc2n(-c3cccc(Cl)c3)c3ccc([N+](=O)[O-])cc3cc-2c(=O)[nH]1

 Synonyms

HLI-98C
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Chemsrc provides HLI-98C(CAS#:317326-90-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of HLI-98C are included as well.>> amp version: HLI-98C

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