Regadenoson

Modify Date: 2024-01-02 14:12:33

Regadenoson Structure
Regadenoson structure
Common Name Regadenoson
CAS Number 313348-27-5 Molecular Weight 390.354
Density 2.0±0.1 g/cm3 Boiling Point N/A
Molecular Formula C15H18N8O5 Melting Point 158-160ºC
MSDS N/A Flash Point N/A

 Use of Regadenoson


Regadenoson is an A2A adenosine receptor agonist that is a coronary vasodilator that is commonly used in pharmacologic stress testing.Target: A2A adenosine receptorRegadenoson produces hyperemia quickly and maintains it for a duration that is useful for radionuclide myocardial perfusion imaging. The selective nature of the drug makes it preferable to other stress agents such as adenosine, which are less selective and therefore cause more side-effects.Regadenoson has a 2 to 3 minute biological half-life.[1]

 Names

Name Regadenoson
Synonym More Synonyms

 Regadenoson Biological Activity

Description Regadenoson is an A2A adenosine receptor agonist that is a coronary vasodilator that is commonly used in pharmacologic stress testing.Target: A2A adenosine receptorRegadenoson produces hyperemia quickly and maintains it for a duration that is useful for radionuclide myocardial perfusion imaging. The selective nature of the drug makes it preferable to other stress agents such as adenosine, which are less selective and therefore cause more side-effects.Regadenoson has a 2 to 3 minute biological half-life.[1]
Related Catalog
References

[1]. Pape M, et al. Safety and tolerability of regadenoson for myocardial perfusion imaging - first Danish experience. Scand Cardiovasc J. 2016 Jun;50(3):180-6.

 Chemical & Physical Properties

Density 2.0±0.1 g/cm3
Melting Point 158-160ºC
Molecular Formula C15H18N8O5
Molecular Weight 390.354
Exact Mass 390.140015
PSA 186.46000
LogP -3.09
Index of Refraction 1.896
Storage condition -20℃

 Synonyms

2-[4-(Methylcarbamoyl)-1H-pyrazol-1-yl]adenosine
Adenosine, 2-[4-[(methylamino)carbonyl]-1H-pyrazol-1-yl]-
Regadenoson
Regadenoson anhydrous
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