4-fluoro-N-phenylbenzenesulfonamide

Modify Date: 2024-01-09 12:36:47

4-fluoro-N-phenylbenzenesulfonamide Structure
4-fluoro-N-phenylbenzenesulfonamide structure
Common Name 4-fluoro-N-phenylbenzenesulfonamide
CAS Number 312-52-7 Molecular Weight 251.27700
Density 1.374g/cm3 Boiling Point 376.7ºC at 760mmHg
Molecular Formula C12H10FNO2S Melting Point N/A
MSDS N/A Flash Point 181.6ºC

 Names

Name 4-fluoro-N-phenylbenzenesulfonamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.374g/cm3
Boiling Point 376.7ºC at 760mmHg
Molecular Formula C12H10FNO2S
Molecular Weight 251.27700
Flash Point 181.6ºC
Exact Mass 251.04200
PSA 54.55000
LogP 3.78030
Index of Refraction 1.618

 MSDS

Material Safety Data Sheet

Section1. Identification of the substance
Product Name: N-Phenyl 4-fluorobenzenesulfonamide
Synonyms:4-Fluoro-N-phenylbenzenesulfonamide

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.

Section3. Composition/information on ingredients.
Ingredient name:N-Phenyl 4-fluorobenzenesulfonamide
CAS number:312-52-7

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Store in closed vessels.
Storage:

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not specified
Boiling point:No data
No data
Melting point:
Flash point:No data
Density:No data
Molecular formula:C12H10FNO2S
Molecular weight:251.3

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides, hydrogen fluoride, sulfur oxides.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DB2660000
CHEMICAL NAME :
Benzenesulfonamide, 4-fluoro-N-phenyl-
CAS REGISTRY NUMBER :
312-52-7
BEILSTEIN REFERENCE NO. :
2810140
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C12-H10-F-N-O2-S
MOLECULAR WEIGHT :
251.29

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 39,514,1984

 Safety Information

HS Code 2935009090

 Synthetic Route

~67%

4-fluoro-N-phenylbenzenesulfonamide Structure

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CAS#:312-52-7

Literature: Cao, Xiangxiang; Bai, Yang; Xie, Yanjun; Deng, Guo-Jun Journal of Molecular Catalysis A: Chemical, 2014 , vol. 383-384, p. 94 - 100

~89%

4-fluoro-N-phenylbenzenesulfonamide Structure

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CAS#:312-52-7

Literature: Pombrik, S. I.; Golovchenko, L. S.; Peregudov, A. S.; Fedin, E. I.; Kravtsov, D. N. Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1986 , vol. 35, # 6 p. 1144 - 1148 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1986 , # 6 p. 1263 - 1267

~%

4-fluoro-N-phenylbenzenesulfonamide Structure

4-fluoro-N-phen...

CAS#:312-52-7

Literature: J. Gen. Chem. USSR (Engl. Transl.), , vol. 37, # 1 p. 163 - 170,149 - 155

~%

4-fluoro-N-phenylbenzenesulfonamide Structure

4-fluoro-N-phen...

CAS#:312-52-7

Literature: J. Gen. Chem. USSR (Engl. Transl.), , vol. 37, # 1 p. 163 - 170,149 - 155

 Customs

HS Code 2935009090
Summary 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

 Synonyms

4-Fluoro-N-Phenyl-Benzenesulfonamide
4-Fluor-benzolsulfanilid
4-Fluor-benzol-sulfon-N-phenyl-amid
N-PHENYL 4-FLUOROBENZENESULFONAMIDE
4-fluorobenzenesulfonanilide
4-fluoro-benzenesulfonic acid anilide
Benzenesulfonanilide,4-fluoro
Benzenesulfonamide,4-fluoro-N-phenyl
4-Fluor-benzolsulfonsaeure-anilid