CCT036477
Modify Date: 2025-08-25 11:04:52
CCT036477 structure
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Common Name | CCT036477 | ||
|---|---|---|---|---|
| CAS Number | 305372-78-5 | Molecular Weight | 347.84100 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H18ClN3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of CCT036477CCT036477 is a selective inhibitor of wingless-type MMTV integration site family (WNT)-dependent transcription. It reduces the transcriptional activity of the T-cell factor/lymphoid enhancer factor transcription factor family at the ?-catenin level. |
| Name | N-[(4-chlorophenyl)-(2-methyl-1H-indol-3-yl)methyl]pyridin-2-amine |
|---|---|
| Synonym | More Synonyms |
| Molecular Formula | C21H18ClN3 |
|---|---|
| Molecular Weight | 347.84100 |
| Exact Mass | 347.11900 |
| PSA | 40.71000 |
| LogP | 5.79920 |
| InChIKey | IFOHRIXRQPOHQZ-UHFFFAOYSA-N |
| SMILES | Cc1[nH]c2ccccc2c1C(Nc1ccccn1)c1ccc(Cl)cc1 |
| RIDADR | NONH for all modes of transport |
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Targeting Wnt pathway in mantle cell lymphoma-initiating cells.
J. Hematol. Oncol. 8 , 63, (2015) Mantle cell lymphoma (MCL) is an aggressive and incurable form of non-Hodgkin's lymphoma. Despite initial intense chemotherapy, up to 50% of cases of MCL relapse often in a chemoresistant form. We hyp... |
| f0388-0065 |