2,4(1H,3H)-Pyrimidinedione,1-b-D-arabinofuranosyl-5-iodo-

Modify Date: 2025-08-27 13:40:20

2,4(1H,3H)-Pyrimidinedione,1-b-D-arabinofuranosyl-5-iodo- structure	Common Name	2,4(1H,3H)-Pyrimidinedione,1-b-D-arabinofuranosyl-5-iodo-
	CAS Number	3052-06-0	Molecular Weight	370.10
	Density	2.27g/cm3	Boiling Point	N/A
	Molecular Formula	C₉H₁₁IN₂O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 2,4(1H,3H)-Pyrimidinedione,1-b-D-arabinofuranosyl-5-iodo-

1-Beta-D-arabinofuranosyl-5-iodouracil is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	1-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-iodo-pyrimidine-2,4-dione
Synonym	More Synonyms

Description	1-Beta-D-arabinofuranosyl-5-iodouracil is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Density	2.27g/cm3
Molecular Formula	C₉H₁₁IN₂O₆
Molecular Weight	370.10
Exact Mass	369.96600
PSA	124.78000
Index of Refraction	1.748

1-β-D-Arabinofu...

CAS#:3083-77-0

~92%

2,4(1H,3H)-Pyri...

CAS#:3052-06-0

Literature: Kumar; Wiebe; Knaus Canadian Journal of Chemistry, 1994 , vol. 72, # 9 p. 2005 - 2010

5-Iodo-2',3',5'...

CAS#:84500-33-4

~80%

2,4(1H,3H)-Pyri...

CAS#:3052-06-0

Literature: Lin, Kun-I.; Chiang, Li-Wu; Wu, Chien-Hung; Chen, Shao-Wei; Yu, Chung-Shan Journal of the Chinese Chemical Society, 2007 , vol. 54, # 2 p. 563 - 568

5-Iodouridine

CAS#:1024-99-3

1-β-D-Arabinofu...

CAS#:3083-77-0

2,4(1H,3H)-Pyri...

CAS#:3052-06-0

Literature: Cech, D.; Schwarz, B.; Pein, C. D. Journal fuer Praktische Chemie (Leipzig), 1983 , vol. 325, # 3 p. 387 - 392

2,2'-Cyclouridine

CAS#:3736-77-4

2,4(1H,3H)-Pyri...

CAS#:3052-06-0

Literature: Lin, Kun-I.; Chiang, Li-Wu; Wu, Chien-Hung; Chen, Shao-Wei; Yu, Chung-Shan Journal of the Chinese Chemical Society, 2007 , vol. 54, # 2 p. 563 - 568

Uridine

CAS#:58-96-8

2,4(1H,3H)-Pyri...

CAS#:3052-06-0

Literature: Lin, Kun-I.; Chiang, Li-Wu; Wu, Chien-Hung; Chen, Shao-Wei; Yu, Chung-Shan Journal of the Chinese Chemical Society, 2007 , vol. 54, # 2 p. 563 - 568

2,4(1H,3H)-Pyri...

CAS#:14057-18-2

2,4(1H,3H)-Pyri...

CAS#:3052-06-0

Literature: Lin, Kun-I.; Chiang, Li-Wu; Wu, Chien-Hung; Chen, Shao-Wei; Yu, Chung-Shan Journal of the Chinese Chemical Society, 2007 , vol. 54, # 2 p. 563 - 568

Precursor 6
CAS#:3083-77-0 1-β-D-Arabinofu... CAS#:84500-33-4 5-Iodo-2',3',5'... CAS#:1024-99-3 5-Iodouridine CAS#:3736-77-4 2,2'-Cyclouridine
CAS#:58-96-8 Uridine CAS#:14057-18-2 2,4(1H,3H)-Pyri...
DownStream 0

5-Iodoarabinouridine

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2,4(1H,3H)-Pyrimidinedione,1-b-D-arabinofuranosyl-5-iodo-

Use of 2,4(1H,3H)-Pyrimidinedione,1-b-D-arabinofuranosyl-5-iodo-

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Precursor & DownStream

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.