Prothipendyl

Modify Date: 2024-01-04 16:42:37

Prothipendyl structure	Common Name	Prothipendyl
	CAS Number	303-69-5	Molecular Weight	285.40700
	Density	1.168g/cm3	Boiling Point	430.8ºC at 760mmHg
	Molecular Formula	C₁₆H₁₉N₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	214.3ºC

Name	N,N-dimethyl-3-pyrido[3,2-b][1,4]benzothiazin-10-ylpropan-1-amine
Synonym	More Synonyms

Density	1.168g/cm3
Boiling Point	430.8ºC at 760mmHg
Molecular Formula	C₁₆H₁₉N₃S
Molecular Weight	285.40700
Flash Point	214.3ºC
Exact Mass	285.13000
PSA	44.67000
LogP	3.70100
Index of Refraction	1.621

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UU8576000

CHEMICAL NAME :: 10H-Pyrido(3,2-b)(1,4)benzothiazine, 10-(3-(dimethylamino)propyl)-

CAS REGISTRY NUMBER :: 303-69-5

BEILSTEIN REFERENCE NO. :: 0259865

LAST UPDATED :: 199706

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C16-H19-N3-S

MOLECULAR WEIGHT :: 285.44

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 25 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 18,373,1963

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 415 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 8,489,1958

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 135 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: STRAAA Strahlentherapie. (Urban & Schwarzenberg, Postfach 202440, D-8000 Munich 2, Fed. Rep. Ger.) V.1- 1912- Volume(issue)/page/year: 127,245,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 102 mg/kg

TOXIC EFFECTS :: Behavioral - antipsychotic

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 149,374,1964 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3040 mg/kg/22W-I

TOXIC EFFECTS :: Related to Chronic Data - death

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 30,1709,1980 *** REVIEWS *** TOXICOLOGY REVIEW ADVPA3 Advances in Pharmacology. (New York, NY) V.1-6, 1962-68. For publisher information, see AVPCAQ. Volume(issue)/page/year: 4,263,1966

HS Code	2934999090

1H-Pyrido[3,2-b...

CAS#:261-96-1

3-Chloro-N,N-di...

CAS#:109-54-6

Prothipendyl

CAS#:303-69-5

Literature: Schuler,W.A.; Klebe,H. Justus Liebigs Annalen der Chemie, 1962 , vol. 653, p. 172 - 180

N/A

CAS#:95873-97-5

Prothipendyl

CAS#:303-69-5

Literature: Yale; Sowinski Journal of the American Chemical Society, 1958 , vol. 80, p. 1651,1653

2-[(3-NITRO-2-P...

CAS#:92316-06-8

Prothipendyl

CAS#:303-69-5

Literature: Yale; Sowinski Journal of the American Chemical Society, 1958 , vol. 80, p. 1651,1653

N-[2-(3-nitropy...

CAS#:91902-18-0

Prothipendyl

CAS#:303-69-5

Literature: Yale; Sowinski Journal of the American Chemical Society, 1958 , vol. 80, p. 1651,1653

2-Aminothiophenol

CAS#:137-07-5

Prothipendyl

CAS#:303-69-5

Literature: Yale; Sowinski Journal of the American Chemical Society, 1958 , vol. 80, p. 1651,1653

2-Anilinopyridine

CAS#:6631-37-4

Prothipendyl

CAS#:303-69-5

Literature: Schuler,W.A.; Klebe,H. Justus Liebigs Annalen der Chemie, 1962 , vol. 653, p. 172 - 180

Dimethylamine

CAS#:124-40-3

1-Bromo-3-chlor...

CAS#:109-70-6

Prothipendyl

CAS#:303-69-5

Literature: DEGUSSA Patent: DE1014544 , 1956 ;

Precursor 8
CAS#:261-96-1 1H-Pyrido[3,2-b... CAS#:109-54-6 3-Chloro-N,N-di... CAS#:92316-06-8 2-[(3-NITRO-2-P... CAS#:91902-18-0 N-[2-(3-nitropy...
CAS#:137-07-5 2-Aminothiophenol CAS#:6631-37-4 2-Anilinopyridine CAS#:124-40-3 Dimethylamine CAS#:109-70-6 1-Bromo-3-chlor...
DownStream 0

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Prothipendyl

Prothipendylum [INN-Latin]

Prothipendyl [INN:BAN]

LG 206

Largophren

Protipendilo [INN-Spanish]

(3-Benzo[b]pyrido[2,3-e][1,4]thiazin-10-yl-propyl)-dimethyl-amin

Tumovan

Timoval

(3-benzo[b]pyrido[2,3-e][1,4]thiazin-10-yl-propyl)-dimethyl-amine

Timovan

Dominal

10-<3-Dimethylamino-propyl>-4-aza-phenothiazin

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Prothipendyl
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Get all suppliers and price by the below link:

Prothipendyl suppliers

Prothipendyl price

Prothipendyl

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Safety Information

Synthetic Route

Precursor & DownStream

Customs

Synonyms