UNII:T875VN0D6E

Modify Date: 2025-08-27 08:29:42

UNII:T875VN0D6E structure	Common Name	UNII:T875VN0D6E
	CAS Number	303-26-4	Molecular Weight	286.80
	Density	1.2±0.1 g/cm3	Boiling Point	409.1±0.0 °C at 760 mmHg
	Molecular Formula	C₁₇H₁₉ClN₂	Melting Point	65-70 °C(lit.)
	MSDS	Chinese USA	Flash Point	193.3±26.5 °C
	Symbol	GHS07	Signal Word	Warning

Use of UNII:T875VN0D6E

1-(4-Chlorobenzhydryl)piperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Name	1-(4-Chlorobenzhydryl)piperazine
Synonym	More Synonyms

Description	1-(4-Chlorobenzhydryl)piperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog	Research Areas >> Others
In Vitro	1-(4-氯苄基)哌嗪是美氯嗪和氯环嗪的无活性代谢物，在羟嗪和西替利嗪的商业制剂中也发现它是一种杂质。1-(4-氯苄基)哌嗪已被用于合成电压门控钠通道 1.7 (Nav1.7) 抑制剂、抗癌剂和抗组胺剂。
References	[1]. Gaertner, HJ, Breyer, U., and Liomin, G.Chronic administration of chlorcyclizine and meclizine to rats: Accumulation of a metabolite formed by piperazine ring cleavage J. Pharmacol. Exp. Ther.185(2)195-201(1973) [2]. Kuntzman, R., Klutch, A., Tsai, I., et al.Physiological distribution and metabolic inactivation of chlorcyclizine and cyclizineJ. Pharmacol. Exp. Ther.149(1)29-35(1965) [3]. Simpson, D., Skellern, GG, and Miller, JHMethod for the control of known impurities in hydroxyzine hydrochlorideJ. Pharm . Biomed. Anal.14(8-10)1371-1375(1996) [4]. Javid, FS, Shafaat, A., and Zarghi, A. Determination of cetirizine and its impurities in bulk and tablet formulation using a validated capillary zone electrophoretic methodJ. Anal. Chem.69(5)442-447(2014) [5]. Back, SK, Kam, YL, Oh, JA, et al.Synthesis and evaluation of (4-chlorobenzhydryl) piperazine amides as sodium channel Nav7 inhibitorsBull. Korean Chem. Soc.36(9)2290-2297(2015) [6]. Yarim, M., Koksal, M., Durmaz, I., et al.Cancer cell cytotoxicities of 1-(4-substitutedbenzoyl)-4 -(4-chlorobenzhydryl)piperazine derivativesInt. J. Mol. Sci.13(7)8071-8085(2012) [7]. Narsaiah, AV, and Narssimha, P.Efficient synthesis of antihistamines clocinizine and chlorcyclizineMed. Chem. Res.21538- 541 (2012)

Density	1.2±0.1 g/cm3
Boiling Point	409.1±0.0 °C at 760 mmHg
Melting Point	65-70 °C(lit.)
Molecular Formula	C₁₇H₁₉ClN₂
Molecular Weight	286.80
Flash Point	193.3±26.5 °C
Exact Mass	286.123688
PSA	15.27000
LogP	3.44
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.592
InChIKey	UZKBSZSTDQSMDR-UHFFFAOYSA-N
SMILES	Clc1ccc(C(c2ccccc2)N2CCNCC2)cc1
Storage condition	Refrigerator

UNII:T875VN0D6E MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TL1772000

CHEMICAL NAME :: Piperazine, 1-(p-chloro-alpha-phenylbenzyl)-

CAS REGISTRY NUMBER :: 303-26-4

BEILSTEIN REFERENCE NO. :: 0243027

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C17-H19-Cl-N2

MOLECULAR WEIGHT :: 286.83

WISWESSER LINE NOTATION :: T6M DNTJ DYR&R DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 100 mg/kg

SEX/DURATION :: female 12-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 147,391,1965

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 500 mg/kg

SEX/DURATION :: female 12-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 147,391,1965

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi:Irritant
Risk Phrases	R36/37/38
Safety Phrases	S26-S37/39-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	TL1772000
HS Code	2933599090

Precursor 7
CAS#:110-85-0 Piperazine CAS#:134-83-8 UNII:LC0K0NYJ2N CAS#:119-56-2 4-Chlorobenzhydrol CAS#:1155402-49-5 phenyl 4-((4-ch...
CAS#:628717-39-5 4-nitrophenyl 4... CAS#:134-85-0 4-Chlorobenzophenone CAS#:104-88-1 4-Chlorobenzaldehyde
DownStream 10
CAS#:1161573-31-4 (R)-(-)-1-[(4-c... CAS#:439858-21-6 1-[(S)-(4-Chlor... CAS#:298-55-5 Clocinizine CAS#:82-93-9 Di-Paralene
CAS#:83881-37-2 Cetirizine Amide CAS#:83881-46-3 Cetirizine meth... CAS#:2192-20-3 Hydroxyzine dih... CAS#:1104-22-9 Meclizine dihyd...
CAS#:109806-71-5 UNII:PGV947X9B1 CAS#:114624-65-6 3-[[4-[(4-chlor...

HS Code	2933599090
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

EINECS 206-137-4

N-(4-CHLOROBENZHYDRYL)-PIPERAZINE

Hydroxyzine Related Compound A

1-(α-Phenyl-4-chlorobenzyl)piperazine

Norchlorcyclizine

1-(4-Chlorobenzhydry)piperazine

1-((4-Chlorophenyl)(phenyl)methyl)piperazine

1-[(4-Chlorophenyl)(phenyl)methyl]piperazine

1-(4-Chlorobenzhydryl) piperazine

1-(4-Chloro-α-phenylbenzyl)piperazine

1-(p-chlorobenzhydryl)piperazine

N-[(4-chlorophenyl)phenylmethyl]piperazine

1-(4-Chlorodiphenylmethyl)piperazine

1-(4-chlorobenzhydryl)-piperazine

1-(4-chlorobenzhydryl)

Piperazine, 1- (p-chloro-α-phenylbenzyl)-

Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-

N-[1-(4-chlorophenyl)-1-(phenyl)methyl]piperazine

MFCD00005965

Piperazine, 1-[α-(4-chlorophenyl)benzyl]-

UNII:T875VN0D6E

4-(4-Chlorobenzhydryl)piperazine

(RS)-1-[(4-Chlorophenyl)phenylmethyl]piperazine

1-[(4-chlorophenyl)phenylmethyl]-piperazine

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: UNII:T875VN0D6E
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: UNII:T875VN0D6E
Price: ￥188.0/1g
Purity: 98.0%
Delivery: 2 Day
Contact: Liu jia
Email: 2130147988@qq.com

DC Chemicals Limited
China
Product Name: Norchlorcyclizine
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1-(4-Chlorobenzhydryl)piperazine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 1-(4-Chlorobenzhydryl)piperazine
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Get all suppliers and price by the below link:

UNII:T875VN0D6E suppliers

UNII:T875VN0D6E price

UNII:T875VN0D6E

Use of UNII:T875VN0D6E

Names

UNII:T875VN0D6E Biological Activity

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Safety Information

Synthetic Route

Precursor & DownStream

Customs

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.