CDD-1733

Modify Date: 2025-08-22 14:55:50

CDD-1733 Structure
CDD-1733 structure
Common Name CDD-1733
CAS Number 2894104-33-5 Molecular Weight 599.65
Density N/A Boiling Point N/A
Molecular Formula C34H32F3N5O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CDD-1733


CDD-1733 is a non-covalent and non-peptide potent SARS-CoV-2 Mpro inhibitor with a Ki of 12 nM. CDD-1733 also inhibits ΔP168, A173V, and ΔP168/A173V Mpro variants[1].

 Names

Name CDD-1733

 CDD-1733 Biological Activity

Description CDD-1733 is a non-covalent and non-peptide potent SARS-CoV-2 Mpro inhibitor with a Ki of 12 nM. CDD-1733 also inhibits ΔP168, A173V, and ΔP168/A173V Mpro variants[1].
Related Catalog
Target

Ki: 12 nM (SARS-CoV-2 Mpro)[1]

References

[1]. Ravikumar Jimmidi, et al. DNA-encoded chemical libraries yield non-covalent and non-peptidic SARS-CoV-2 main protease inhibitors. Commun Chem. 2023 Aug 4;6(1):164.  

 Chemical & Physical Properties

Molecular Formula C34H32F3N5O2
Molecular Weight 599.65
InChIKey FOWCQWSLGBHNCT-WWGLSMKPSA-N
SMILES CCCC(NC(=O)c1cccc2nc(-c3cncc4ccccc34)n(C3CC(C(=O)NC)C3)c12)c1ccc(C(F)(F)F)cc1
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