GBD-9
Modify Date: 2024-01-04 02:15:17
GBD-9 structure
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Common Name | GBD-9 | ||
|---|---|---|---|---|
| CAS Number | 2864408-92-2 | Molecular Weight | 797.90 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C44H47N9O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of GBD-9GBD-9 is a double-mechanism degrader that efficiently degrades BTK and GSPT1 by recruiting the E3 ligase cereblon (CRBN). GBD-9 acts both as a PROTAC molecule to induce the degradation of BTK and as a molecular glue to degrade GSPT1. GBD-9 effectively inhibits cancer cell growth[1]. |
| Name | GBD-9 |
|---|
| Description | GBD-9 is a double-mechanism degrader that efficiently degrades BTK and GSPT1 by recruiting the E3 ligase cereblon (CRBN). GBD-9 acts both as a PROTAC molecule to induce the degradation of BTK and as a molecular glue to degrade GSPT1. GBD-9 effectively inhibits cancer cell growth[1]. |
|---|---|
| Related Catalog | |
| Target |
Cereblon |
| References |
| Molecular Formula | C44H47N9O6 |
|---|---|
| Molecular Weight | 797.90 |