sevoflurane

Modify Date: 2025-08-20 13:16:40

sevoflurane structure	Common Name	sevoflurane
	CAS Number	28523-86-6	Molecular Weight	200.055
	Density	1.4±0.1 g/cm3	Boiling Point	49.5±35.0 °C at 760 mmHg
	Molecular Formula	C₄H₃F₇O	Melting Point	50-60ºC
	MSDS	Chinese USA	Flash Point	-11.4±21.8 °C
	Symbol	GHS07	Signal Word	Warning

Name	sevoflurane
Synonym	More Synonyms

Density	1.4±0.1 g/cm3
Boiling Point	49.5±35.0 °C at 760 mmHg
Melting Point	50-60ºC
Molecular Formula	C₄H₃F₇O
Molecular Weight	200.055
Flash Point	-11.4±21.8 °C
Exact Mass	200.007217
PSA	9.23000
LogP	2.48
Vapour Pressure	311.5±0.1 mmHg at 25°C
Index of Refraction	1.266
InChIKey	DFEYYRMXOJXZRJ-UHFFFAOYSA-N
SMILES	FCOC(C(F)(F)F)C(F)(F)F

sevoflurane MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KO0737000

CHEMICAL NAME :: Ether, fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl-

CAS REGISTRY NUMBER :: 28523-86-6

LAST UPDATED :: 199612

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C4-H3-F7-O

MOLECULAR WEIGHT :: 200.07

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,591,1990

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 28800 ppm/3H

TOXIC EFFECTS :: Behavioral - tremor Lungs, Thorax, or Respiration - cyanosis Skin and Appendages - hair

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 21,5497,1987

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 6300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,591,1990

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 18200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,591,1990

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 28300 ppm/3H

TOXIC EFFECTS :: Behavioral - tremor Lungs, Thorax, or Respiration - cyanosis Skin and Appendages - hair

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 21,5497,1987

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 10500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,591,1990 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 6600 ppm/3H

SEX/DURATION :: male 64 day(s) pre-mating female 14 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 21,5505,1987

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 2 pph/3H

SEX/DURATION :: male 9 week(s) pre-mating female 2 week(s) pre-mating female 1-7 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females)

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 21,5505,1987

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 1 pph/3H

SEX/DURATION :: male 9 week(s) pre-mating female 2 week(s) pre-mating female 1-7 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :: KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 21,5505,1987

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319
Precautionary Statements	P305 + P351 + P338
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36/37/39
RIDADR	UN 3334
RTECS	KO0737000

Precursor 9
CAS#:26103-07-1 Chloromethyl-1,... CAS#:373-53-5 Fluor(iod)methan CAS#:920-66-1 Hexafluoroisopr... CAS#:373-52-4 Bromofluoromethane
CAS#:593-70-4 Chlorofluoromethane CAS#:406-58-6 1,1,1,3,3-Penta... CAS#:50-00-0 Formaldehyde CAS#:1152045-94-7 methyl 3,3,3-tr...
CAS#:97614-43-2 2-Deoxy-2-fluor...
DownStream 3
CAS#:26103-07-1 Chloromethyl-1,... CAS#:13171-18-1 Hexafluoroisopr... CAS#:58109-34-5 1,1,3,3,3-Penta...

Propofol increases morbidity and mortality in a rat model of sepsis.

Crit. Care 19 , 45, (2015)

Severe sepsis is associated with approximately 50% mortality and accounts for tremendous healthcare costs. Most patients require ventilatory support and propofol is commonly used to sedate mechanicall...

Protective effect of curcumin against contrast induced nephropathy in rat kidney: what is happening to oxidative stress, inflammation, autophagy and apoptosis?

Eur. Rev. Med. Pharmacol. Sci. 18(4) , 461-70, (2014)

Currently, the number of imaging and interventional procedures that use contrast agents (CAs) is gradually increasing. Oxidative stress plays a significant role in its pathophysiology. Curcumin (CC) i...

Generation of suppressive blood cells for control of allograft rejection.

Clin. Sci. 128(9) , 593-607, (2015)

Our previous studies in rats showed that incubation of monocytic dendritic cells (DCs) with the chemotherapeutic drug mitomycin C (MMC) renders the cells immunosuppressive. Donor-derived MMC-DCs injec...

Sevoness

Sevofrane

R-E 347

mr6s4

Fluoromethyl 1,1,1,3,3,3-hexafluoropropan-2-yl ether

347mmzEbg

fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether

Ultane

oxyde de fluorométhyle et de 2,2,2-trifluoro-1-(trifluorométhyl)éthyle

Sevoflurane

Propane, 1,1,1,3,3,3-hexafluoro-2-(fluoromethoxy)-

Sevorane

1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane

Fluormethyl-2,2,2-trifluor-1-(trifluormethyl)ethylether

Fluoromethyl 1,1,1,3,3,3-hexafluoro-2-propyl ether

MFCD00153189

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: sevoflurane
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: sevoflurane
Price: ￥2108.0/5g ￥658.0/1g ￥3508.0/25g
Purity: 98.0%
Delivery: Inquiry
Contact: Liu jia
Email: 2130147988@qq.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Sevoflurane
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Get all suppliers and price by the below link:

sevoflurane suppliers

sevoflurane price

sevoflurane

Names

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Safety Information

Synthetic Route

Precursor & DownStream

Articles135

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.