MRL-1237
Modify Date: 2025-09-19 14:57:23
MRL-1237 structure
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Common Name | MRL-1237 | ||
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| CAS Number | 276704-21-3 | Molecular Weight | 354.813 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H16ClFN4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MRL-1237MRL-1237 is a potent and selective inhibitor of the replication of Enteroviruses with EC50 of 1-10 uM, targets the nonstructural 2C protein; inhibits poliovirus-specific RNA synthesis in HeLa cells infected with a wild strain but not with an F164Y mutant. |
| Name | MRL-1237 |
|---|
| Description | MRL-1237 is a potent and selective inhibitor of the replication of Enteroviruses with EC50 of 1-10 uM, targets the nonstructural 2C protein; inhibits poliovirus-specific RNA synthesis in HeLa cells infected with a wild strain but not with an F164Y mutant. |
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| References | References 1. Shimizu H, et al. J Virol. 2000 May;74(9):4146-54. 2. De Palma AM, et al. J Virol. 2008 May;82(10):4720-30. View Related Products by Target Enterovirus |
| Molecular Formula | C19H16ClFN4 |
|---|---|
| Molecular Weight | 354.813 |
| InChIKey | OQLKNESERKFJAI-UHFFFAOYSA-N |
| SMILES | Cl.N=c1ccn(Cc2nc3ccccc3n2-c2ccc(F)cc2)cc1 |