Mpro/PLpro-IN-1

Modify Date: 2024-01-04 15:28:13

Mpro/PLpro-IN-1 structure	Common Name	Mpro/PLpro-IN-1
	CAS Number	2766185-78-6	Molecular Weight	466.96
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₂₇ClN₄O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Mpro/PLpro-IN-1

Mpro/PLpro-IN-1 (Compound 29) is a potent inhibitor of Mpro/PLpro. Mpro/PLpro-IN-1 is a dual acting SARS-CoV-2 proteases inhibitor featuring micromolar inhibitory potency versus Mpro (IC50 = 1.72 μM) and submicromolar potency versus PLpro (IC50 = 0.67 μM)[1].

Name	Mpro/PLpro-IN-1

Description	Mpro/PLpro-IN-1 (Compound 29) is a potent inhibitor of Mpro/PLpro. Mpro/PLpro-IN-1 is a dual acting SARS-CoV-2 proteases inhibitor featuring micromolar inhibitory potency versus Mpro (IC50 = 1.72 μM) and submicromolar potency versus PLpro (IC50 = 0.67 μM)[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Others >> Others
References	[1]. Di Sarno V, et al. Identification of a dual acting SARS-CoV-2 proteases inhibitor through in silico design and step-by-step biological characterization. Eur J Med Chem. 2021;226:113863.

Molecular Formula	C₂₅H₂₇ClN₄O₃
Molecular Weight	466.96
InChIKey	DMHYAQLYAFULCU-VXKWHMMOSA-N
SMILES	C=CCC(NC(=O)CCl)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCc1ccccc1

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Mpro/PLpro-IN-1

Use of Mpro/PLpro-IN-1

Names

Mpro/PLpro-IN-1 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.