TNG908

Modify Date: 2025-08-25 12:37:41

TNG908 Structure
TNG908 structure
Common Name TNG908
CAS Number 2760481-53-4 Molecular Weight 409.50
Density N/A Boiling Point N/A
Molecular Formula C21H23N5O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TNG908


TNG908 is a MTAP-cooperative PRMT5 inhibitor that can pass through the blood-brain barrier. TNG908 is 15 times more selective for MTAP null cell lines than MTAPWT cell lines, and can be used in cancer research[1].

 Names

Name TNG908

 TNG908 Biological Activity

Description TNG908 is a MTAP-cooperative PRMT5 inhibitor that can pass through the blood-brain barrier. TNG908 is 15 times more selective for MTAP null cell lines than MTAPWT cell lines, and can be used in cancer research[1].
Related Catalog
References

[1]. K. Briggs, et al. TNG908 is a brain-penetrant, MTA-cooperative PRMT5 inhibitor for the treatment of MTAP-deleted cancer.MOLECULAR TARGETED AGENTS 2| VOLUME 174, SUPPLEMENT 1, S84, OCTOBER 2022.

 Chemical & Physical Properties

Molecular Formula C21H23N5O2S
Molecular Weight 409.50
InChIKey NXXBDYHMHHINFC-YVEFUNNKSA-N
SMILES Cc1cc(NC(=O)C(=O)N2CC(C)CCC2c2ccc3scnc3c2)cnc1N
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.